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Annual Report 2011 - Center for Advanced Biotechnology and ...

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12:30 PM Lunch <strong>and</strong> Break<br />

Kamana Misra – Molecular Neurodevelopment Lab (Meng Xiang)<br />

“To be or not to be" A neuron's perspective<br />

2:15 PM Posters <strong>and</strong> Coffee<br />

4:30 PM Close<br />

Session III – Underst<strong>and</strong>ing Disease at the Molecular Level as a Basis <strong>for</strong> Developing<br />

Novel Therapies<br />

Chair: Kamana Misra – Molecular Neurodevelopment Lab (Meng Xiang)<br />

Mary Fitzgerald Ho – Biomolecular Crystallography Lab (Eddy Arnold)<br />

“GE23077: A novel bacterial RNA polymerase inhibitor”<br />

Joseph Marcotrigiano – Structural Virology Lab (Joe Marcotrigiano)<br />

“The Structure of a Precursor from the Alphavirus Replication Complex sheds light on<br />

pathogenesis <strong>and</strong> mechanisms of polyprotein processing”<br />

Rongjin Guan – Structural Bioin<strong>for</strong>matics <strong>and</strong> Proteomics Lab (Guy Montelione)<br />

“Structural Basis <strong>for</strong> the Sequence-Specific Recognition of Human ISG15 by the NS1 Protein<br />

of Influenza B Virus”<br />

Yu Meng – Protein Targeting Lab (Peter Lobel)<br />

“Intravenous enzyme replacement therapy <strong>for</strong> late-infantile neuronal ceroid lipofuscinosis<br />

(LINCL)”<br />

Fang Liu – Growth <strong>and</strong> Differential Lab (Fang Liu)<br />

“Pin1 promotes TGF-beta-induced migration <strong>and</strong> invasion”<br />

Na Yang – Tumor Virology Lab (Céline Gélinas)<br />

“Underst<strong>and</strong>ing <strong>and</strong> targeting Bfl-1 turnover to overcome chemoresistance”<br />

72

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