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Coatings - AkzoNobel

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Developments in the Business Units<br />

ORGANON – PRESCRIPTION DRUGS<br />

Sales NLG 2,880 million (1997: NLG 2,540 million)<br />

Another successful year for 75-year-old Organon<br />

Organon celebrated its 75th anniversary in 1998.<br />

Mr. Saal van Zwanenberg founded Organon in Oss, the<br />

Netherlands, in 1923. From its modest beginnings<br />

Organon has grown into a well-regarded and respected<br />

healthcare company with almost 10,000 employees<br />

(including 1,500 in R&D), having subsidiaries in<br />

55 countries and selling its products in virtually every<br />

country in the world.<br />

In 1998, Organon achieved a 13 percent increase in<br />

sales and a significantly higher operating income.<br />

In Europe, sales rose 10 percent. Growth rates of more<br />

than 25 percent were achieved in France, Spain,<br />

Sweden, Denmark, and—in Eastern Europe—the Czech<br />

Republic, Slovakia, and Rumania. In the Americas sales<br />

increased 38 percent, with the United States as the star<br />

performer at 67 percent growth. In Asia we faced a<br />

setback in sales of about 20 percent due to the<br />

economic and financial crisis. In Australia we did<br />

exceptionally well, with sales rising by 35 percent.<br />

Sales growth by product group breaks down as follows:<br />

Contraception 5 percent, Hormone Replacement<br />

Therapy (HRT) 15 percent, Fertility 33 percent, and<br />

Central Nervous System (CNS) 52 percent. In<br />

Contraception the final outcome in the scientific debate<br />

about the second and third generation oral<br />

contraceptives was: there is no difference in the<br />

prevalence of thrombosis. The political outcome in one<br />

country remains uncertain.<br />

In the United States, Mircette® oral contraceptive was<br />

launched, and its acceptance looks very positive. In HRT<br />

we continue to develop our unique tissue-specific Livial®<br />

brand into a leading product in the market of<br />

treatments of climacteric complaints and prevention of<br />

osteoporosis. In Fertility our rapidly growing<br />

Puregon®/Follistim® recombinant FSH product was very<br />

successful. In CNS we have the ambition to increase the<br />

worldwide market share of our novel Remeron®<br />

antidepressant to 6 percent by the year 2000.<br />

AKZO NOBEL ANNUAL REPORT 1998<br />

27<br />

PHARMA<br />

Our R&D focuses on innovation, with 16 to 17 percent<br />

of sales being spent in this field. New R&D facilities are<br />

under construction or planned in the United Kingdom,<br />

the United States, and the Netherlands. Our R&D<br />

strategy is to establish contacts with outside centers of<br />

excellence, simultaneously building a high quality,<br />

creative, and competitive R&D organization.<br />

In Processing, we are concentrating our efforts on<br />

efficiency and improvement of equipment to meet high<br />

quality requirements. Production facilities in France,<br />

Spain, and Korea were sold to third parties.<br />

Besides our R&D and Processing efforts, we will<br />

continue to focus on:<br />

• HSE: implementing ISO 14001 standards;<br />

• competitive intelligence: using contemporary IT facilities<br />

to optimize business decisions;<br />

• health economics: demonstrating cost-effectiveness to<br />

convince new decision-makers;<br />

• Information Technology: integrating business functions<br />

and facilitating international communication;<br />

• logistics: creating higher customer-added value and<br />

optimizing inventories;<br />

• time-to-market: reducing the time lag between<br />

regulatory approval, price approval, and product<br />

launch.<br />

ORGANON TEKNIKA – HOSPITAL SUPPLIES<br />

Sales NLG 1,010 million (1997: NLG 950 million)<br />

Strong volume growth<br />

Strong volume growth was the striking feature in 1998,<br />

for both Pharmaceuticals and Diagnostics. Operating<br />

income was well ahead of 1997. Sales and operating<br />

income were negatively impacted by lower rates for<br />

various currencies, such as the yen and the U.S. dollar<br />

that declined in the second half of 1998, and by the<br />

recession in Southeast Asia.<br />

R&D focuses on Pharmaceuticals, mainly for<br />

anesthesiologists, and on the special Diagnostics fields<br />

of Immunodiagnostics, Microbiology, Hemostasis, and<br />

Nucleic Acid Diagnostics. Organon Teknika’s<br />

international headquarters were moved in November<br />

1998 from Turnhout, Belgium, to Boxtel, the<br />

Netherlands, and integrated with the European R&D,<br />

manufacturing, and distribution facilities to improve<br />

operational efficiency.

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