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Developments in the Business Units<br />
ORGANON – PRESCRIPTION DRUGS<br />
Sales NLG 2,880 million (1997: NLG 2,540 million)<br />
Another successful year for 75-year-old Organon<br />
Organon celebrated its 75th anniversary in 1998.<br />
Mr. Saal van Zwanenberg founded Organon in Oss, the<br />
Netherlands, in 1923. From its modest beginnings<br />
Organon has grown into a well-regarded and respected<br />
healthcare company with almost 10,000 employees<br />
(including 1,500 in R&D), having subsidiaries in<br />
55 countries and selling its products in virtually every<br />
country in the world.<br />
In 1998, Organon achieved a 13 percent increase in<br />
sales and a significantly higher operating income.<br />
In Europe, sales rose 10 percent. Growth rates of more<br />
than 25 percent were achieved in France, Spain,<br />
Sweden, Denmark, and—in Eastern Europe—the Czech<br />
Republic, Slovakia, and Rumania. In the Americas sales<br />
increased 38 percent, with the United States as the star<br />
performer at 67 percent growth. In Asia we faced a<br />
setback in sales of about 20 percent due to the<br />
economic and financial crisis. In Australia we did<br />
exceptionally well, with sales rising by 35 percent.<br />
Sales growth by product group breaks down as follows:<br />
Contraception 5 percent, Hormone Replacement<br />
Therapy (HRT) 15 percent, Fertility 33 percent, and<br />
Central Nervous System (CNS) 52 percent. In<br />
Contraception the final outcome in the scientific debate<br />
about the second and third generation oral<br />
contraceptives was: there is no difference in the<br />
prevalence of thrombosis. The political outcome in one<br />
country remains uncertain.<br />
In the United States, Mircette® oral contraceptive was<br />
launched, and its acceptance looks very positive. In HRT<br />
we continue to develop our unique tissue-specific Livial®<br />
brand into a leading product in the market of<br />
treatments of climacteric complaints and prevention of<br />
osteoporosis. In Fertility our rapidly growing<br />
Puregon®/Follistim® recombinant FSH product was very<br />
successful. In CNS we have the ambition to increase the<br />
worldwide market share of our novel Remeron®<br />
antidepressant to 6 percent by the year 2000.<br />
AKZO NOBEL ANNUAL REPORT 1998<br />
27<br />
PHARMA<br />
Our R&D focuses on innovation, with 16 to 17 percent<br />
of sales being spent in this field. New R&D facilities are<br />
under construction or planned in the United Kingdom,<br />
the United States, and the Netherlands. Our R&D<br />
strategy is to establish contacts with outside centers of<br />
excellence, simultaneously building a high quality,<br />
creative, and competitive R&D organization.<br />
In Processing, we are concentrating our efforts on<br />
efficiency and improvement of equipment to meet high<br />
quality requirements. Production facilities in France,<br />
Spain, and Korea were sold to third parties.<br />
Besides our R&D and Processing efforts, we will<br />
continue to focus on:<br />
• HSE: implementing ISO 14001 standards;<br />
• competitive intelligence: using contemporary IT facilities<br />
to optimize business decisions;<br />
• health economics: demonstrating cost-effectiveness to<br />
convince new decision-makers;<br />
• Information Technology: integrating business functions<br />
and facilitating international communication;<br />
• logistics: creating higher customer-added value and<br />
optimizing inventories;<br />
• time-to-market: reducing the time lag between<br />
regulatory approval, price approval, and product<br />
launch.<br />
ORGANON TEKNIKA – HOSPITAL SUPPLIES<br />
Sales NLG 1,010 million (1997: NLG 950 million)<br />
Strong volume growth<br />
Strong volume growth was the striking feature in 1998,<br />
for both Pharmaceuticals and Diagnostics. Operating<br />
income was well ahead of 1997. Sales and operating<br />
income were negatively impacted by lower rates for<br />
various currencies, such as the yen and the U.S. dollar<br />
that declined in the second half of 1998, and by the<br />
recession in Southeast Asia.<br />
R&D focuses on Pharmaceuticals, mainly for<br />
anesthesiologists, and on the special Diagnostics fields<br />
of Immunodiagnostics, Microbiology, Hemostasis, and<br />
Nucleic Acid Diagnostics. Organon Teknika’s<br />
international headquarters were moved in November<br />
1998 from Turnhout, Belgium, to Boxtel, the<br />
Netherlands, and integrated with the European R&D,<br />
manufacturing, and distribution facilities to improve<br />
operational efficiency.