Among the companies that expandedtheir in-state operations, the largestpercentage credited the skilledworkforce for that decision (Figure12). High marks also were given forthe culture of entrepreneurship orinnovation in <strong>California</strong>. Many also arestaying and growing here because this iswhere their companies were founded.Among companies that cut operationsin <strong>California</strong> over the past year, 20percent cited “cost-cutting initiatives” astheir motive (Figure 13). The other topcited reasons were business decline andlack or loss of private funding — both at16 percent.Over the past year, the surveyrespondents reported much moreanemic growth in their out-of-state andforeign operations, although growthdid exceed reductions in all categoriesexcept G&A staffing.Looking ahead 24 months, respondentsanticipate solid growth for their<strong>California</strong> operations (Figure 15) andslow or flat growth for their out-of-Figure 11: 2011 CEO Survey: Have the following activities expanded, held steadyor reduced for the company’s operations inside <strong>California</strong> in the past year?Held steadyReducedExpandedResearchanddevelopment35%22%43%Manufacturing58%13%29%General andadministrative53%24%24%Overallworkforce34%26%40%Figure 12: 2011 CEO Survey: Which of the following are the factors influencingyour decision to locate or expand your operations inside <strong>California</strong>?Skilled workforce 36%History of founders/<strong>California</strong> is where the company was founded 31%Culture of entrepreneurship or innovation 31%Access to leading research universities 28%Quality of life 26%Access to pharmaceutical, biotech, device and diagnostics companies 23%Access to funding or capital 21%Pro-business environment or commitment to the industry 9%Tax incentives 8%Cost of doing business 7%Alliance with other leading <strong>California</strong> industries 6%Other 4%Cost of living 4%State commitment to education funding 1%Figure 13: 2011 CEO Survey: Select the reasons why the company’s operationshave reduced inside <strong>California</strong> in the past year.Cost cutting initiative 20%Business slowdown or decline 16%Lack or loss of private funding 16%Overall business climate/cost of doing business 13%Expanded new operations outside of <strong>California</strong> 8%Lack of tax incentives or unfavorable tax environment 6%Cost of living 6%Other 6%Moved existing operations outside of <strong>California</strong> 4%Qualified workforce elsewhere 4%Sold or consolidated a portion of the business 3%Other regions offering free or less expensive land/infrastructure for expansion 3%Attractive state funding, grants, or investments elsewhere 1%12 | <strong>California</strong> <strong>Biomedical</strong> <strong>Industry</strong> 2011 Report
state operations (Figure 16). For thefirst time in the history of this report,more respondents intend to increasemanufacturing in <strong>California</strong> versusbeyond the state’s borders —41 percent versus 21 percent. Further,companies are expecting to increasetheir workforces overall and across allcategories.With the world’s most comprehensivenetwork of research and higher learningcenters, entrepreneurs, employers,investors and suppliers in place,<strong>California</strong> is well positioned to sustainand even grow its highly specializedand well compensated workforce. Thestrength of the biomedical sector’scontributions to the state’s employmentis evident in the number of jobsretained through a significant economicdownturn and the need and desireof the industry’s leading innovatorsto continue to grow their <strong>California</strong>operations.Figure 14: 2011 CEO Survey: Have the following activities expanded, held steadyor reduced for the company’s operations outside <strong>California</strong> in the past year?Will expandWill hold steadyWill reduceResearch anddevelopment60%16%23%Manufacturing71%9%20%General andadministrative76%14%10%Overallworkforce53%16%31%Figure 15: 2011 CEO Survey: Do you anticipate that the following activities willexpand, hold steady or be reduced for the company’s operations inside <strong>California</strong>in the next two years?Will expandWill hold steadyWill reduceResearch anddevelopment62%26%12%Manufacturing41%42%17%General andadministrative45%40%15%Overallworkforce68%19%13%Figure 16: 2011 CEO Survey: Do you anticipate that the following activitieswill expand, hold steady or be reduced for the company’s operations outside<strong>California</strong> in the next two years?Will expandWill hold steadyWill reduceResearch anddevelopment25%59%16%Manufacturing21%69%9%General andadministrative10%76%14%Overallworkforce31%52%16%PerspectiveLife sciences sector construction to build steamThe pace of job creation in <strong>California</strong>was expected to pick up in the fourthquarter of 2010, according to anindicator published in early Novemberfrom the A. Gary Anderson Centerfor Economy Research at ChapmanUniversity. However, the trends inconstruction spending offer less causefor optimism. <strong>California</strong> constructionspending, which shrank 30.1 percent inthe third quarter of 2010, was the onlycomponent that continued to be weak.Despite this tough backdrop, on anational basis job creation by U.S. lifesciences employers continues to grow.As the industry continues to grow,so do requirements for laboratoryfacilities, making new life scienceconstruction one of the few bright spotsin the construction world. AlexandriaReal Estate Equities, Inc. — therecognized world-wide leader of labspace development — has continuedto develop life science real estatethroughout the economic downturn,given resilient demand in Alexandria’sbest-in-class adjacency locations. Asan example, the company’s projects inMission Bay, San Francisco continueto move forward, and recently signedleading life science tenants includeBayer, Celgene and UCSF, to name afew. Additionally, Alexandria continuesto work with its general contractors tocomplete site work that will expeditefuture building deliveries oncesignificant pre-leasing is completed.As the industry recovers, Alexandria willstrategically adapt to meet its growingspace needs, and play a pivotal rolesupporting the in creation of future jobsin the life science construction sector.<strong>California</strong> <strong>Biomedical</strong> <strong>Industry</strong> 2011 Report | 13