Methamphetamine29decline in their ability to function in social and job-relatedsituations. (This inability can persist for months or yearseven after stopping use.)One of the most devastating effects of methamphetamineaddiction can be seen in pregnant women who are addicted.Exposure of a fetus to methamphetamine has been shown tocause limb malformations, abnormal reflexes, and behavioralproblems in the newborn. Moreover, meth-addicted expectantmothers experience more premature deliveries and complicationsduring delivery than do non-using expectant mothers.Another consequence of methamphetamine addiction isincreased risk for HIV infection and AIDS, since many methusers inject the drug intravenously and share needles. In fact,illegal drug use is one of the fastest-growing ways HIV is spreadto other people.Once a methamphetamine addict stops taking the drug,the withdrawal symptoms can be very severe and includedepression and anxiety, increased appetite, fatigue, paranoia,irritability, aggressive behavior, and intense craving for thedrug. Some of these symptoms can be eased with sedativedrugs like Valium or antidepressants like Prozac®.Although there are currently no pharmacological treatmentsfor methamphetamine addiction, psychological treatmentssuch as psychotherapy, cognitive-behavioral therapy (whichinvolves changing one’s thought patterns, expectations, andbehavior), and improving coping skills can be mildly effectivein helping meth addicts stay clean.
3EcstasyCOMMON STREET NAMESX, XTC, E, Adam, Eve, Clarity,Stacy,Love drug,Lover’s Speed,HugDrug, Versace, Essence, Decadence, Dex, M&M, Roll, Bean,Bens, B-Bombs, Disco Biscuit, Go, Morning Shot, Scooby Snacks,Sweeties, Wheels.HISTORY AND LEGAL STATUSEcstasy, also known by its chemical name, 3,4-methylenedioxymethamphetamine(MDMA), was first synthesized in 1912 bychemists at the Merck pharmaceutical company in Germany, whowere searching for amphetamine analogues to use as new appetitesuppressants. These chemists also synthesized a similar drug called3,4-methylenedioxyamphetamine (MDA), which, as it turns out, isan active metabolite of MDMA. As MDMA and MDA are veryclosely related to amphetamine and methamphetamine (Figure 3.1),Ecstasy is considered one of the original “designer drugs.”Merck patented MDMA and MDA in 1914, but World Wars Iand II sidetracked any further research on the drugs. Interest in thetwo drugs was revived in the 1950s by the U.S. military, but neverwent further than the animal testing stage.Ecstasy remained largely unused as a recreational drugthrough the 1960s and early 1970s. However, in the late 1970s, abiochemist at the University of California at Berkeley namedAlexander Shuglin was approached by a student who claimed tohave used MDMA to fix a stuttering problem. Shuglin decidedto synthesize the drug and take it himself. He wrote a scientific30
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Painkiller Analogues79Figure 7.4 Th
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Painkiller Analogues81the brain tha
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Bibliography and Further ReadingCha
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Dillon, P. Copel, and J.K. Jansen.
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www.projectghb.orgInformation about
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Talk With Your KidsInformation on t
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Date rape drugsEcstasy, 37GHB, 43,
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Picture Creditspage:13: Lambda Scie