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Ru 486 Misconceptions Myths and Morals - ressourcesfeministes

Ru 486 Misconceptions Myths and Morals - ressourcesfeministes

Ru 486 Misconceptions Myths and Morals - ressourcesfeministes

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What Is RU <strong>486</strong> <strong>and</strong> How Does It Work?dexamethasone was administered for two days (Laue et al.,1990:1477). Another research team, Nieman et al. (1985)expressed concern about glucocorticoid insufficiency,suggesting that due to measurement difficulties, RU <strong>486</strong>should be given ‘in concert with careful evaluation for signs<strong>and</strong> symptoms of adrenal insufficiency’ (p. 539). Fatigue,abdominal pain, nausea, dizzy spells or fainting, togetherwith increased susceptibility to infection or physical stress,have been observed following prolonged steroid therapy.Alarmingly, these are some of the symptoms mentioned bywomen after they have taken RU <strong>486</strong>. Régine Sitruk-Ware etal., in their small study of ten women given RU <strong>486</strong>, questionedwhether ‘the asthenia [loss of energy] <strong>and</strong> weakness noted inall subjects represent subjective evidence of glucocorticoiddeficiency’ (1985:247). Similarly, Healy <strong>and</strong> Hodgen ask if‘such an antiglucocorticoid effect may complicate anaesthesia<strong>and</strong> recovery’ in the woman who ‘needs curettage after anRU <strong>486</strong>-induced abortion’ (1985:137). In other words, thehealth of the five to six per cent of women for whom RU <strong>486</strong>/PG abortion fails may be further jeopardized during theirsecond (conventional) abortion.Baulieu maintains that no adverse effects result fromblocking cortisol action at the hypothalamus-pituitary level.He further remarks that should any sign of cortisolinsufficiency ‘unfortunately’ appear, it could easily bereversed by glucocorticosteroid administration (1985:19).We contend this is another familiar example of bad medicalpractice where one drug’s adverse effects are countered withthe prescription of yet another. Baulieu suggests that ‘the useof RU <strong>486</strong> in a provocative test for the exploration of thebrain-pituitary-adrenal system may be of great interest toanalyze some aspects of the neuroendocrine functioning…’(idem.). Provocative <strong>and</strong> of great interest for whom we mightask? Who gains laurels 12 <strong>and</strong> who pays the price?The antiglucocorticosteroid property of RU <strong>486</strong> has ledto the claim that it might be used in the treatment of69

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