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Ru 486 Misconceptions Myths and Morals - ressourcesfeministes

Ru 486 Misconceptions Myths and Morals - ressourcesfeministes

Ru 486 Misconceptions Myths and Morals - ressourcesfeministes

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The Role of Prostagl<strong>and</strong>ins: Known <strong>and</strong> Unknown DangersRU <strong>486</strong>. We would contend, of course, that there simplywould not be any PG requirement, were RU <strong>486</strong> the ‘miraclepill’ its supporters proclaim.RU <strong>486</strong> advocates have capitalized on the inequitablest<strong>and</strong>ards operative in the management of women’sreproductive health, to have women believe that ‘RU <strong>486</strong><strong>and</strong> a small dose of prostagl<strong>and</strong>in’ is a superior, safe <strong>and</strong> effectivealternative to conventional abortion methods. The intentionin the following section is to increase readers’ perception ofthe importance of naturally-occurring PGs in reproductivehealth, with a view to establishing an ‘informed’ resistanceto the continuing abuse of women’s bodies in pregnancyrelatedprocedures.The Role <strong>and</strong> Application of Prostagl<strong>and</strong>ins inObstetrics <strong>and</strong> GynecologyPGs were initially discovered in human semen, where theyare probably regulated by progesterone to influence sperm<strong>and</strong> egg transport. PGE levels within seminal fluid may beimportant in male fertility, <strong>and</strong>, due to theirimmunosuppressive properties, may act to protect the spermcomponent of the fertilized ovum from immune attack thatwould result in its destruction at or before the time of itsuterine implantation.Contrary to their limited influence on male reproduction,PGs play a pivotal role in the regulation of women’sreproductive biology. Abnormalities in natural PGproduction are associated with a number of gynecological<strong>and</strong> obstetrical disorders, including primary dysmenorrhea(menstrual cramps). Events which are PG dependent arecervical softening in the final stages of pregnancy, <strong>and</strong>(independent of pregnancy) uterine contractions, the initiationof ovarian follicular growth <strong>and</strong> rupture, egg cell maturation,<strong>and</strong> corpus luteum formation <strong>and</strong> rupture. Though ovarianprocesses are chiefly regulated by hormones, the hormoneeffects are probably modulated by PGs. 387

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