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Research Institutes, Centres and Units - Universiti Sains Malaysia

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International linkages<br />

As we gain the track record in technology innovation <strong>and</strong> product development, we have<br />

gained the attention of Finlay Institute, Havana, Cuba that would like to collaborate with<br />

us to develop diagnostics for third world countries. We currently sealed the collaboration<br />

by forming smart partnerships in the development of diagnostics for typhoid, cholera,<br />

dysentery <strong>and</strong> tuberculosis using monoclonal antibodies <strong>and</strong> Immunochromatography<br />

technology platforms. A grant of RM 3 million has been allocated to achieve these goals.<br />

In the quest of developing cheap micro-fluidicsdiagnostics in terms of a universal PCR<br />

disc, a device has been developed in collaboration with Deakin University, Australia.<br />

The device can be used to replace the conventional PCR machine for DNA diagnostics<br />

<strong>and</strong> deliver results within 30 minutes.<br />

In terms of pharmacogenomics, we have a strong collaboration with Yale University<br />

in the development <strong>and</strong> advancement of pharmacogenomics especially in relation to<br />

AIDS. Other collaborations include with the University of Western Australia in Perth,<br />

African Institute of Biotechnology in Zimbabwe <strong>and</strong> Universitas Gadja Mada in Indonesia.<br />

Grant Acquisitions<br />

Thus far based on our track record, we were able to acquire grants from national<br />

<strong>and</strong> international funding agencies <strong>and</strong> institutions. We were also fortunate to obtain<br />

recognition from the industry <strong>and</strong> the <strong>Malaysia</strong>n Venture Capitalists. We have thus far<br />

been able to attain a total of USD 4 million from government grants, USD 368,000<br />

from 3 European.<br />

Union Grants <strong>and</strong> Bill <strong>and</strong> Melinda Gates Foundation at USD 65,000 . We have also<br />

created a mark with the local business community <strong>and</strong> received contract research<br />

grants of USD79,167 for bioequivalent studies.<br />

Sustainable Health: Development of Rapid Diagnostics for Third World<br />

Countries<br />

The world market for in vitro diagnostics was about USD30 billion dollars in 2000<br />

with nearly 50% based on biotechnology. (Technology Review, Helsinki). It has been<br />

predicted that molecular diagnostics <strong>and</strong> genomics will be seeing the greatest growth<br />

in the next 5-10 years time due to faster development turn around time, requires<br />

minimal regulatory barriers <strong>and</strong> can have competitive production cost. It is imperative<br />

to note that diagnostics developed canbe focused on diseases that would benefit<br />

<strong>Malaysia</strong> <strong>and</strong> the Asian region since the current diagnostics available do not focus on<br />

Asian needs. What is also important to note is that diagnostics made for Asian needs<br />

would also be required by the Latin American market. Hence diagnostics addressing<br />

Asian problems can also have high sales volume since half the world’s population is<br />

located in this region. Even though investigative diagnostics are important to find the<br />

infected individual so as to provide treatment <strong>and</strong> control the spread of an outbreak,<br />

yet annually, 1 million people die of malaria, 4.3 million of Acute respiratory infections,<br />

2.9 million from enteric infections, 5 million of AIDS <strong>and</strong> tuberculosis. Millions still die

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