D7 - Uro,Endocrine

Pathology of endocrine systemadrenal cortexPheochromocytoma(193)frequent in adults• neuroendocrine tumor of medulla of adrenal gland• secretes excessive amounts of catecholamines• hypertensive crisesPheochromocytoma (193)tumor cells with ample finely granular cytoplasm, nuclear atypiaPathology of endocrine systemCarcinoid (184)• neuroendocrine active tumor• colon, interstinum, bronchus, pancreas, other..• serotonin, calikrein... „carcinoid syndrome “Pheochromocytoma (193)• Skin flushing - The skin on face and upper chest changes colorfrom pink to red to purple with the feeling of „heat“. Flushing episodeslast from 30 to 60 seconds• Flushing can be provoked by eating or drinking alcohol• Facial skin lesions• Diarrhea. Frequent, watery stools accompanied by painfulabdominal cramps• Asthma-like signs and symptomssolid nests of uniform, small tumor cellsC A R C I N O I DmucosaCarcinoid in large intestineCarcinoid – colon (184)11