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MDR Bacterial Infections Our Treatment Option

MDR bacteria our treatment option RCPT Khon Kaen - นพ.อมร ลีลารัศมี

MDR bacteria our treatment option RCPT Khon Kaen - นพ.อมร ลีลารัศมี

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Early Combination Rx vs. Monotherapyin Septic ShockCombination Rx MonoRx• ICU admission 352/1,223 (28.8%) 437/1,223 (35.7%)• Odds ratio 0.75• 95% CI 0.63-0.92 (p = .0006)• Hospital mortality 457/1,223 (37.4%) 584/1,223 (47.8%)• Odds ratio 0.69• 95% CI 0.59-0.81 (p < .0001)Kumar A, Zarychanski R, Light B, Parrillo J, Maki D, Simon D, Laporta D, et al. Early combination antibiotic therapy yields improvedsurvival compared with monotherapy in septic shock: a propensity-matched analysis. Crit Care Med 2010;38:1773-85.

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