MDR Bacterial Infections Our Treatment Option
MDR bacteria our treatment option RCPT Khon Kaen - นพ.อมร ลีลารัศมี
MDR bacteria our treatment option RCPT Khon Kaen - นพ.อมร ลีลารัศมี
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Early Combination Rx vs. MonotherapyCombination Rx MonoRxVentilator-free day• Median 17 10• Interquartile range 0-26 0-25 (p = .008)Pressor/inotrope-free day• Median 25 23• Interquartile range 0-28 0-28 (p = .007)up to 30 daysEarly combination antibiotic therapy is associated with decreasedmortality in septic shockProspective randomized trials are neededin Septic ShockKumar A, Zarychanski R, Light B, Parrillo J, Maki D, Simon D, Laporta D, et al. Early combination antibiotic therapy yields improvedsurvival compared with monotherapy in septic shock: a propensity-matched analysis. Crit Care Med 2010;38:1773-85.