BULLETIN
CSQ-Bulletin93
CSQ-Bulletin93
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Page 18 | Bulletin 93 | September 2015<br />
www.niaa-hsrc.org.uk<br />
■■<br />
Patients under the care of an<br />
anaesthetist undergoing general,<br />
regional or local anaesthesia and/or<br />
sedation.<br />
■■<br />
Reactions occurring between<br />
administration of the first drug by<br />
the anaesthetist up to the time of<br />
discharge from the recovery room.<br />
■■<br />
Allergic and non-allergic<br />
(anaphylactoid) reactions.<br />
■■<br />
All ages.<br />
■■<br />
England, Northern Ireland, Scotland<br />
and Wales.<br />
There are four components to NAP6:<br />
1. Baseline Survey for<br />
Anaesthetists:<br />
5 November 2015<br />
In this survey we will ask all<br />
anaesthetists to provide a limited<br />
amount of specific information about<br />
their experience with perioperative<br />
anaphylaxis during the previous 12<br />
months. Data will be anonymised.<br />
2. Baseline Survey for Allergy<br />
Clinics:<br />
5 November 2015<br />
Allergy clinics in the UK will be asked<br />
to provide information about the<br />
services they provide to patients with<br />
suspected perioperative anaphylaxis.<br />
3. Main data collection:<br />
5 November 2015 for 1 year<br />
Detailed, anonymised information<br />
will be collected about every case of<br />
suspected Grade 3-5 perioperative<br />
anaphylaxis in the UK, including<br />
presentation, initial management,<br />
investigation and long-term adverse<br />
sequelae.<br />
4. Activity (allergen) Survey:<br />
April 2016<br />
As with the NAP5 activity survey, every<br />
anaesthetist will be asked to collect<br />
data for each patient they anaesthetise<br />
during a specified two-day period. The<br />
survey will not duplicate data collected<br />
in NAP5 but will collect numerical<br />
information about perioperative<br />
exposure to potential allergens,<br />
including certain anaesthetic drugs,<br />
antibiotics, IV colloids etc. This survey<br />
will act as a denominator to inform<br />
conclusions regarding the relative risks<br />
of anaphylaxis.<br />
The important role of Local<br />
Coordinators<br />
The format of NAP6 will be similar to<br />
previous NAPs: in every UK hospital,<br />
anaesthetists will report their cases to<br />
a Local Coordinator (LC), a consultant<br />
colleague who has volunteered for this<br />
role. The RCoA is extremely grateful<br />
to LCs, without whom these important<br />
national audit projects would be<br />
impossible. LCs will be responsible for<br />
coordinating the reponses to the baseline<br />
survey and the activity survey, as well as<br />
publicising NAP6 within their hospital.<br />
Every UK anaesthetic department will<br />
be asked to nominate a consultant<br />
anaesthetist for this role. This could<br />
be someone who has fulfilled this role<br />
during a previous NAP, or a consultant<br />
who has a particular interest in<br />
perioperative anaphylaxis, for example.<br />
What will happen to the data?<br />
Only anonymized data will be collected<br />
at all stages of the project. Data will be<br />
held on a secure server with passwordprotected<br />
access with the appropriate<br />
regulatory approvals. The NAP6 team<br />
extracting the data and the NAP6<br />
reviewing panel will be unaware of the<br />
identity of the patient, the hospital<br />
and the anaesthetist(s). The reviewing<br />
panel will include anaesthetists,<br />
allergists, immunologists and patient<br />
representatives. Each case reported<br />
during the main data-collection period<br />
will be discussed by the reviewing panel<br />
with reference to the presenting clinical<br />
features, suspected trigger agent,<br />
management, referral for subsequent<br />
investigation, eventual diagnosis, and<br />
the advice given by the allergy clinic to<br />
the patient and the anaesthetist. Where<br />
published guidelines exist, comparisons<br />
will be drawn, but the main purpose of<br />
NAP6 is descriptive.<br />
Publishing the results<br />
A comprehensive report will be<br />
published in early 2018. The results of<br />
the baseline surveys may be published at<br />
an earlier date. The report will include<br />
detailed analysis of the pattern of UK<br />
perioperative anaphylaxis, as well as<br />
pointing to potential improvements in<br />
avoidance, diagnosis and management.<br />
Please look out for further<br />
information relating to NAP6, and<br />
be prepared for the start of this<br />
exciting project on 5 November.<br />
We would be delighted to receive<br />
your comments and answer any<br />
questions you may have about the<br />
project.