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“The observations of this study as well as those of similar studies<br />

suggest that vaccine failures contributed to the genesis of the epidemic.”<br />

Canadian Medical Association Journal • November 1975<br />

Analysis of a measles epidemic:<br />

possible role of vaccine failures<br />

W. E. Rawls, M. L. Rawls, and M. A. Chernesky<br />

Abstract<br />

A measles epidemic occurred in the Greensville (Ont.) Unit schools during<br />

January and February 1975. There were 47 cases of measles in 403<br />

students: 26 (55%) of the children had a history of being vaccinated<br />

and 18 (38%) had not been vaccinated. Among children known to have<br />

been vaccinated at less than 1 year of age 7 of 13 contracted measles,<br />

while among the 48 children who had not been vaccinated 18 contracted<br />

measles. The attack rate among vaccinees increased with increasing<br />

time since vaccination. The observations of this study as well as those<br />

of similar studies suggest that vaccine failures contributed to the genesis<br />

of the epidemic. It is recommended that all children initially vaccinated<br />

at less than 1 year of age should be revaccinated with live attenuated<br />

measles virus vaccine.<br />

Full Report<br />

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1956577/

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