VACCINE

Vaccine • January 2011
Guillain-Barré syndrome after Gardasil vaccination:
data from Vaccine Adverse Event Reporting System
2006-2009
Author information
Souayah N1, Michas-Martin PA, Nasar A,
Krivitskaya N, Yacoub HA, Khan H, Qureshi AI.
Department of Neurology
University of Medicine and Dentistry of New Jersey
Newark, NJ 07103, USA
souayani@umdnj.edu
“The estimated weekly reporting rate
of post-Gardasil Guillain-Barré Syndrome
within the first 6 weeks (6.6 per 10,000,000)
was higher than that of the general population,
and higher than post-Menactra and
post-influenza vaccinations.”
Abstract
Using data from Vaccine Adverse Event Reporting System, we identified 69 reports
of Guillain-Barré Syndrome (GBS) after Gardasil vaccination that occurred
in the United States between 2006 and 2009. The onset of symptoms was within
6 weeks after vaccination in 70% of the patients in whom the date of vaccination
was known. The estimated weekly reporting rate of post-Gardasil GBS within the
first 6 weeks (6.6 per 10,000,000) was higher than that of the general population,
and higher than post-Menactra and post-influenza vaccinations. Further prospective
active surveillance for accurate ascertainment and identification of high-risk
groups of GBS after Gardasil vaccination is warranted.
[for every 100 million women vaccinated
it is known and recognized that there will
be an estimated 66 cases of collateral damage
in the form of Guillain-Barré Syndrome]
http://www.ncbi.nlm.nih.gov/pubmed/?term=20869467