Staff Members of the Institute of Biochemistry, TU - Institut für ...

Invited Lectures
1) A genomic and structural view of flavin-dependent proteins. International conference on
cofactors, 14. July 2011, Turku, Finland
2) From structure-based flavoenzymology to functional flavogenomics. Colloquium at the
Max F. Perutz Laboratory - Vienna Biocentre, 27. October 2011, Vienna, Austria
Publications
1) Schrittwieser, J. H., Resch, V., Sattler, J., Lienhart, W.-D., Durchschein, K., Winkler,
A., Gruber, K., Macheroux, P., and Kroutil, W.: Biocatalytic enantioselective oxidative
C-C coupling by aerobic C-H activation of N-CH3 to yield novel berberine alkaloid
derivatives, Angew. Chem. Int. Ed., 2011, 50:1068-1071.
2) Schittmayer, M., Glieder, A., Uhl, M. K., Winkler, A., Zach, S., Schrittwieser, J.,
Kroutil, W., Macheroux, P., Gruber, K., Kambourakis, S., Rozzell, J. D., Winkler, M.:
Old Yellow Enzyme catalyzed dehydrogenation of saturated ketones, Adv. Synth.
Catal., 2011, 353:268-274.
3) Durchschein, K., Fabian, W. M. F., Macheroux, P., Zangger, K., Trimmel, G., Faber,
K.: Reductive biotransformation of nitroalkenes via nitroso-intermediates to oxazetes
catalyzed by xenobiotic reductase A (XenA), Org. Biomol. Chem., 2011, 9:3364-3369.
4) Gesell, A., Chavez, M. L. D., Kramell, R., Piotrowski, M., Macheroux, P., and Kutchan,
T. M.: Heterologous expression of two FAD-dependent oxidases with (S)tetrahydroprotoberberine
oxidase activity from Argemonas mexicana and Berberis
wilsoniae in insect cells, Planta, 2011, 233:1185-1197.
5) Macheroux, P., Kappes, B., and Ealick, S. E.: Flavogenomics: A genomic and structural
view on flavin-dependent proteins, FEBS J., 2011, 278:2625-2634.
6) Schrittwieser, J. H., Resch, V., Wallner, S., Lienhart, W.-D., Sattler, J. H., Resch, J.,
Macheroux, P., Kroutil, W.: Biocatalytic organic synthesis of optically pure (S)scoulerine
and novel berbine and benzylisoquinoline alkaloids, J. Org. Chem., 2011,
76:6703-6714.
7) Schober, M., Gadler, P., Knaus, T., Kayer, H., Birner-Grünberger, R., Gülly, C.,
Macheroux, P., Wagner, U., Faber, K.: A stereoselective inverting sec-alkylsulfatase for
the deracemisation of sec-alcohols, Org. Lett., 2011, 13:4296-4299.
8) Resch, V., Schrittwieser, J. H., Wallner, S., Macheroux, P., Kroutil, W.: Biocatalytic
oxidative carbon-carbon bond formation catalysed by berberine bridge enzyme: optimal
reaction conditions, Adv. Synth. Catal., 2011, 353:2377-2383.
9) Kappes, B., Tews, I., Binter, A., Macheroux, P.: PLP-dependent enzymes as potential
drug targets for protozoan diseases, Biophys. Biochem. Acta, 2011, 1814:1567-1576.
10) Binter, A., Oberdorfer, G., Hofzumahaus, S., Nerstheimer, S., Altenbacher, G., Gruber,
K., Macheroux, P.: NikK is a pyridoxal 5’-phosphate dependent enzyme in nikkomycin
biosynthesis, FEBS J., 2011, 278:4122-4135.
11) Jankowitsch, F., Kühm, C., Kellner, R., Kalinowski, J., Pelzer, S., Macheroux, P., and
Mack, M.: RosA is a novel N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase
catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces
davawensis, J. Biol. Chem., 2011, 286:38275-38285.
14