Natural_Medicine_Magazine_Issue_145_July_2017

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KEEPING IN TOUCH References 1. Anand P., Sundaram C., et al. Curcumin and cancer: an ‘old-age’ disease with an ‘ageold’ solution. Cancer Lett Aug 2008; 267(1):133- 164. 2. Jurenka JS Antiinflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev June 2009; 14(2):141-153. 3. Menon VP, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol 2007; 595:105-125. 4. Zhang L, Fiala M, et al. Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer’s disease patients. J Alzheimers Dis Sep 2006; 10(1):1-7. THERAPEUTIC BENEFITS Curcumin and cancer As discussed in my interview with Professor Dan Burke in our last issue, curcumin has distinct anti-cancer mechanisms. Research shows that curcumin can inhibit the growth and spread of cancer at a molecular level. 1 These tests in the laboratory are encouraging although further study is needed to verify whether or not high doses of curcumin can help to treat people with cancer or prevent it. A powerful anti-inflammatory Although short-term inflammation is necessary for the repair and healing of damaged tissue, long-term, low-level inflammation plays a major part in the onset of many serious Western diseases such as diabetes, heart disease and Alzheimer’s disease. Curcumin is a highly effective anti-inflammatory, as effective in fact as some anti-inflammatory drugs. 2 Its efficacy lies in its ability to block a molecule that activates genes related to inflammation. Further study is however necessary to determine whether or not curcumin can slow down or reverse Alzheimer’s disease. Curcumin as an immunomodulatory agent At low doses curcumin enhances antibody responses. This ability to modulate the immune system would be an added benefit curcumin gives to the healing process. Here cancer patients in particular could benefit as most anticancer drugs have immunosuppressive side effects. Curcumin has absolutely no immunosuppressive effects and laboratory tests show that it also restores the immune system. ENHANCING CURCUMIN’S BIOAVAILABILITY Curcumin presents a challenge when it comes to its poor bioavailability, in other words the amount that is successfully absorbed in order for it to be effective. High oral doses of the substance to counteract this poor bioavailability are not an option because of concerns of toxicity. Turmeric has been used as an anti-inflammatory in India for thousands of years. A powerful antioxidant Antioxidants protect the body from free radicals. Curcumin is far more effective an antioxidant than -tocopherol: It neutralises free radicals directly and then stimulates the body’s own antioxidant enzymes. 3 Traditionally turmeric is mixed with milk or butter and eaten. It can be combined with oil and applied topically to injured areas to reduce swelling, pain and infection. A solution to the problem of poor bioavailability can be found in a powerful curcumin extract that encourages curcumin's absorption and beneficial effects. A reduction in oxidative stress protects against heart disease and Alzheimer’s disease. Curcumin inhibits LDL-cholesterol oxidation, which is thought to mark the start of the hardening of the arteries. Studies have also shown that curcumin also clears plaque build-up, or protein tangles, which are indicative of Alzheimer’s. 4 To sum up: Enjoy turmeric as a healthy spice in your cooking and invest in a worthwhile curcumin supplement to assist you along your path to good health. The references listed here are for additional information and interest. 012 | NATURALMEDICINE.CO.ZA
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