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Entering the digital era Global Investor, 02/2012 Credit Suisse

Entering the digital era
Global Investor, 02/2012
Credit Suisse

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GLOBAL INVESTOR 2.12 — 21<br />

Photos: Thomas Eugster | Cédric Widmer<br />

we model physiological interactions and<br />

<br />

mental<br />

components of the organism.<br />

What will the virtual patient look like?<br />

Denis Hochstrasser: There are<br />

<br />

USA, uses personal health<br />

information to visualize three-dimensional,<br />

interactive anatomical models of individuals<br />

that run on the iPad or iPhone. Nhumi,<br />

a spin-off of IBMware<br />

plug-ins for displaying virtual human<br />

<br />

physical exercise and having your avatar<br />

<br />

your medical history and genomic makeup.<br />

The virtual patient is actually part of<br />

a larger project called ITFoM (Information<br />

Tech nology Future of Medicine) that is<br />

competing for funding from the European<br />

<br />

<br />

Hans Lehrach: In Europe, we spend<br />

around 11% of GDP on medical treatment.<br />

<br />

of aging societies. Moreover, people<br />

<br />

at the same time they stopped working<br />

under Bismarck. And as we are finding out,<br />

longer living does not necessarily translate<br />

into healthier living. We have a very strong<br />

economic incentive to try and change<br />

the healthcare system.<br />

It’s going to take an enormous amount<br />

of computing power, isn’t it?<br />

Hans Lehrach:<br />

<br />

of a weather report for 500 million Europeans.<br />

We know that, for every patient coming<br />

<br />

tion<br />

of the capacity of a nuclear reactor.<br />

It comes down to how much extra information<br />

and computing power will save you<br />

how much on the medical side.<br />

What do the skeptics say?<br />

Denis Hochstrasser: They say, with<br />

some reason, that the greatest advance in<br />

modern medicine was hand washing. Losing<br />

<br />

would cutting down on alcohol and giving up<br />

smoking. Not ITFoM. But the two are not<br />

mutually exclusive. People do not see themselves<br />

as they are. With a medical avatar that<br />

evolves as a person gets older, they might.<br />

Hans Lehrach: We are currently<br />

<br />

per year, generating many more data than<br />

Hans Lehrach <br />

<br />

<br />

<br />

we did in the entire ten years of the genome<br />

project. In my view, that information<br />

<br />

than the 28% we have in clinical practice.<br />

<br />

cine<br />

now. It’s clear that our models initially<br />

<br />

<br />

<br />

expect from ITFoM?<br />

Hans Lehrach:<br />

tualize drug development. For example,<br />

pharma companies could take drugs<br />

that have failed in clinical trials and get<br />

<br />

patients that actually respond to them.<br />

That would not just save costs and reduce<br />

risks. It would also save time. Look, a drug<br />

patent lasts 20 years. If you can cut the<br />

time to development, which typically is 19<br />

years, to 6 using this type of virtualization,<br />

<br />

<br />

<br />

What does ITFoM mean for ordinary<br />

humans?<br />

Hans Lehrach: If you give people a<br />

computer model of themselves that allows<br />

them to test what will happen if they don’t<br />

jog regularly and watch their diet, that’s<br />

relevant to them. Empowering people to<br />

have more control over themselves is a positive<br />

development and potentially more<br />

far-reaching than making classical medicine<br />

more efficient.<br />

<br />

example of you doing rounds at the hospital,<br />

<br />

Denis Hochstrasser: Instead of me waiting<br />

for the computer to download PDF files,<br />

it shows me an image of the patient and<br />

-<br />

<br />

a toe infection. I go to each of these alerts,<br />

<br />

<br />

the proper therapies with confidence<br />

<br />

edge<br />

and all the knowledge we have<br />

-<br />

<br />

<br />

<br />

<br />

Sounds useful.<br />

Denis Hochstrasser:

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