Final Programme
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118<br />
Posters Physicians Tuesday, 31 March 2009<br />
17:30– Immunotherapy<br />
19:00<br />
P899 Generation of WT1 peptide-specific T-cells out of healthy volunteer donors for<br />
adoptive immunotherapy after allogeneic stem cell transplantation<br />
G. Weber, J. Karbach, S. Kuci, H. Kreyenberg, A. Willasch, T. Klingebiel, W. Wels, E. Jäger,<br />
P. Bader (Frankfurt, DE)<br />
P900 Human alloreactive CD4+ T-cells as potent effector cells and sole mediators of<br />
anti-tumour responses in a NOD/Scid mouse model for human acute leukaemia<br />
S. Stevanovic, M. Griffioen, B.A. Nijmeijer, M.L.J. Van Schie, R. Willemze,<br />
J.H.F Falkenburg (Leiden, NL)<br />
P901 The composition and quality of leukaemia-derived dendritic cells,T-cells and the<br />
cellular microenvironment is predictive for the antileukaemic T-cell cytotoxic<br />
reactions of DC-primed T-cells and the response to therapy<br />
H. Schmetzer, A. Liepert, C. Grabrucker, D. Fischbacher, M. Merle, M. Freudenreich,<br />
F. Schuster, S. Reuther, A. Kremser, J. Loibl, R. Reibke, C. Schmid, T. Kroell, H.J. Kolb<br />
(Munich, Augsburg, DE)<br />
P902 The use of steroids but not T-cell recovery disturbs reconstitution of NK cell<br />
receptor repertoire after alloHSCT<br />
S. Giebel, J. Dziaczkowska, T. Czerw, J. Wojnar, M. Krawczyk-Kulis, I. Nowak,<br />
A. Holowiecka-Goral, A. Segatti, S. Kyrcz-Krzemien, J. Holowiecki, P. Kusnierczyk<br />
(Gliwice, Katowice, Wroclaw, PL; Pavia, IT)<br />
P903 Chemotherapy before donor lymphocyte infusion enhances lymphocyte activation<br />
and induces clinical responses<br />
G.F. Torelli, R. Maggio, W. Barberi, N. Peragine, M.S. De Propris, A.P. Iori, V. Valle,<br />
E. Iannella, F. Natalino, E. Arleo, A. Guarini, R. Foà (Rome, IT)<br />
P904 Clinical grade generation of human anti-adenovirus-cytotoxic T-cells for adoptive<br />
immunotherapy<br />
L. Aissi-Rothe, V. Decot, C. Mathieu, A. Kennel, V. Venard, H. Jeulin, A. Salmon,<br />
L. Clement, P. Bordigoni, J.F. Stoltz, D. Bensoussan (Vandoeuvre Les Nancy, FR)<br />
P905 CXCL8 and CCL2 secretion by dendritic cells generated from AML-blasts (DCleu)<br />
as well as IFN-g or IL-6 release in mixed lymphocyte cultures from T-cells after<br />
DC-priming are predictive for antileukaemic T-cell reactions<br />
D. Fischbacher, M. Merle, A. Liepert, C. Grabrucker, A. Kremser, J. Loibl, C. Schmid,<br />
T. Kroell, H.J. Kolb, H.M. Schmetzer (Munich, Augsburg, DE)<br />
P906 Immune response of human propagated gd-T-cells to neuroblastoma recommend<br />
the Vd1 subset for gd-T-cell based immunotherapy<br />
K. Schilbach, K. Frommer, S. Meier, R. Handgretinger, M. Eyrich (Tübingen, DE)<br />
P907 Priming and expansion of HLA-B*0702/CMV_pp65 restricted CTL for adoptive<br />
immunotherapy by use of artifical antigen presenting complexes is essentially<br />
influenced by differential triggering of co-stimulatory pathways<br />
M. Kapp, K. Fick, S. Jackob, M. Oelke, R. Thiele, E. Baumeister, S.M. Tan, H. Wajant,<br />
J.P. Schneck, A. Opitz, H. Einsele, G. Grigoleit (Würzburg, DE; Baltimore, US)<br />
P908 Assessment of signalling events in antigen-specific T-cells by combining<br />
phosphoepitope specific flow cytometry and MHC-multimer staining<br />
R. Thiele, M. Kapp, E. Baumeister, K. Fick, G. Stuhler, A. Opitz, H. Einsele, G. Grigoleit<br />
(Würzburg, DE)<br />
P909 Escalating doses of donor lymphocytes to rescue from rejection following bone<br />
marrow transplantation for thalassaemia<br />
I. Frugnoli, B. Cappelli, R. Chiesa, A. Noè, E. Biral, S. Gattillo, T. Roccia, C. Evangelio,<br />
M. Fossati, S. Napolitano, A. Giardelli, C. Soliman, F. Ciceri, M.G. Roncarolo, S. Marktel<br />
(Milan, IT)
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