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News<br />

Metabolix to cooperate<br />

with Antibióticos<br />

Metabolix, Inc. (Cambridge, Massachusetts, USA),<br />

announced end of July that it has signed a letter of intent<br />

(LOI) with Antibióticos S.A. for production of Mirel<br />

biopolymer resin (PHA) at its manufacturing facility in<br />

Leon, Spain.<br />

Under the terms of the LOI, Metabolix will begin work<br />

immediately with Antibióticos to conduct a series of<br />

validation production runs to demonstrate fermentation<br />

and recovery of Mirel biopolymer resin on full productionscale<br />

equipment at Antibióticos. The companies plan to<br />

enter into a definitive contract manufacturing agreement<br />

for Mirel biopolymers based upon the validation<br />

production runs as well as completion of economic and<br />

engineering feasibility studies. Metabolix will own the<br />

Mirel biopolymer resin produced during the validation<br />

production runs.<br />

“The agreement with Antibióticos represents a<br />

significant step forward in establishing a new supply<br />

chain for Mirel biopolymers to serve our customers<br />

worldwide and to continue product development in<br />

high value-added applications,” said Richard P. Eno,<br />

president and chief executive officer of Metabolix. “In<br />

addition, Antibióticos is located in the European Union<br />

near many of our targeted customers. We are impressed<br />

with the track record, technical expertise and facilities at<br />

Antibioticos, and believe their equipment is well-suited<br />

to the manufacturing process used to produce Mirel<br />

biopolymers at commercial scale.”<br />

“This agreement brings together our experience<br />

and technical capacity with Metabolix’s technology and<br />

processes in a way that supports the values and vision<br />

of both companies,” said Daniele Pucci Di Benisichi,<br />

president of Antibióticos. “The first step of our work<br />

with Metabolix will be to validate their technology in our<br />

facility. Then, we’ll look ahead to creating a contract<br />

manufacturing agreement. Antibióticos follows a very<br />

demanding and selective approach for new projects and<br />

partners, and we’re particularly pleased to be working<br />

with Metabolix to deepen our work in sustainable<br />

technologies and diversify our business portfolio.”<br />

Mirel biopolymers are based on polyhydroxyalkanoates<br />

(PHA), biobased, uniquely biodegradable, and suitable<br />

for a wide range of product applications. Metabolix<br />

has previously demonstrated production of Mirel<br />

biopolymer resin at industrial scale. Metabolix<br />

is currently supplying Mirel biopolymer resin to<br />

customers from existing inventory of approximately<br />

2,300 tonnes (5 million pounds). MT<br />

www.metabolix.com<br />

www.antibioticos-sa.com<br />

Bio-based acrylic acid<br />

Presently, acrylic acid is produced by the oxidation<br />

of propylene derived from the refining of crude oil.<br />

BASF (Ludwigshafen, Germany), Cargill (Minneapolis,<br />

Minnesota, USA) and Novozymes (Copenhagen, Denmark)<br />

signed an agreement in mid-August to develop bio-based<br />

technologies to produce acrylic acid from renewable<br />

feedstocks.<br />

“The cooperation combines BASF’s global market<br />

strength and innovation power with the excellent knowhow<br />

and competencies of Novozymes and Cargill who<br />

are global leaders in their respective industry segments.<br />

Together we are uniquely positioned to more sustainably<br />

meet market and society needs”, said Michael Heinz,<br />

Member of the Board of Executive Directors of BASF SE.<br />

New milestone towards commercialization<br />

Novozymes and Cargill have collaborated on renewable<br />

acrylic acid technology since 2008. Both companies have<br />

worked to develop microorganisms that can efficiently<br />

convert renewable feedstock into 3-hydroxypropionic<br />

acid (3-HP), which is one possible chemical precursor<br />

to acrylic acid. BASF has now joined the collaboration to<br />

develop the process for conversion of 3-HP into acrylic<br />

acid. BASF is the world´s largest producer of acrylic<br />

acid and has substantial capabilities in its production<br />

and downstream processing. The company plans<br />

initially to use the bio-based acrylic acid to manufacture<br />

superabsorbent polymers.<br />

The three companies bring complementary knowledge<br />

to the project. Novozymes, the world-leader in industrial<br />

enzymes, has years of experience with developing<br />

technologies for bio-based production of chemicals used<br />

in plastics, ingredients, etc.. Cargill brings its global<br />

expertise in sourcing renewable feedstocks and largescale<br />

fermentation to this collaborative project.<br />

Acrylic acid is a high-volume chemical that feeds into<br />

a broad range of products. One of the main applications<br />

is in the manufacture of superabsorbent polymers that<br />

can soak up large amounts of liquid and are used mainly<br />

in baby diapers and other hygiene products. Acrylic acid<br />

is also used in adhesive raw materials and coatings. The<br />

annual global market volume of acrylic acid is around<br />

4.5 million tons with a value of $11 billion 1 at the end of<br />

2011. The market has been growing at a rate of 4 percent<br />

per year. MT<br />

www.basf.com.<br />

www.cargill.com<br />

www.novozymes.com.<br />

1<br />

Based on ICIS pricing<br />

bioplastics MAGAZINE [05/12] Vol. 7 5

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