International Journal of Noni Research - Noni Family
International Journal of Noni Research - Noni Family
International Journal of Noni Research - Noni Family
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N. Mathivanan et al. Chemical and biological properties <strong>of</strong> Morinda spp.<br />
extract provided considerable protection to the liver cell membrane against<br />
toxic metabolites formed due to D-gal administration. The protective effect was<br />
more pronounced in M. citrifolia than M. pubescens.<br />
Antidiabetic activity <strong>of</strong> M. citrifolia and M. pubescens<br />
i) Body weight <strong>of</strong> the animal<br />
Significant weight loss was observed in diabetic rats as compared to non-diabetic<br />
control animals. The treatment <strong>of</strong> Morinda alcoholic extracts significantly improved<br />
the animal weight as compared to diabetic animals (Table 8).<br />
ii) Hepatic markers<br />
The blood glucose level was significantly increased in alloxan administered<br />
diabetic rats as compared to the non-diabetic control rats (Table 9).<br />
Administration <strong>of</strong> alcoholic extracts <strong>of</strong> M. citrifolia and M. pubescens<br />
significantly decreased the blood glucose level as compared to diabetic control<br />
animals. There was considerable increase in the blood bilirubin level in the<br />
diabetic rats administrated with alcoholic extracts <strong>of</strong> both the species compared<br />
to diabetic control rats. Also there was a considerable alteration in SGPT, SGOT<br />
and ALP levels <strong>of</strong> liver tissue in diabetic rats compared to control and diabetic<br />
rats administrated with alcoholic extracts <strong>of</strong> M. citrifoliaand M. pubescens. The<br />
total protein, albumin and globulin in blood serum were considerably altered<br />
in diabetic rats compared to drug control and diabetic rats administrated with<br />
alcoholic extract <strong>of</strong> M. citrifolia and M. pubescens(Table 9).<br />
Table 5. Rate <strong>of</strong> respiration in fungal pathogens<br />
Pathogen<br />
Rate <strong>of</strong> respiration (Mol./h/min)<br />
Control M. citrifolia M. pubescens<br />
Bipolaris oryzae 97.8 61.3 58.2<br />
Fusarium udum 134.4 72.3 89.2<br />
Curvularia lunata 200.2 82.4 127.3<br />
Phytophthora infestans 250.2 94.5 92.1<br />
Macrophomina phaseolina 124.3 71.2 82.2<br />
Intl. J. <strong>Noni</strong> Res. 2007, 2(1-2) 68
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