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International Journal of Noni Research - Noni Family

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73 Intl. J. <strong>Noni</strong> Res. 2007, 2(1-2)<br />

Fig. 3. Antioxidative activity <strong>of</strong> chlor<strong>of</strong>orm fruit extracts<br />

<strong>of</strong> Morinda spp. (TBA)<br />

iii) Antioxidant activity<br />

There was significant elevation <strong>of</strong> lipid peroxidation and significant reduction<br />

<strong>of</strong> reduced glutathione (GSH), glutathione-S-transferase (GST), superoxide<br />

dismutase (SOD), catalase (CAT) in the liver and kidney <strong>of</strong> diabetic rats as<br />

compared with non-diabetic control rats. Administration <strong>of</strong> alcoholic extracts<br />

<strong>of</strong> M. citrifolia and M. pubescens decreased the levels <strong>of</strong> lipid peroxidation<br />

and elevated the levels <strong>of</strong> GSH, GST, SOD and CAT in liver and kidney <strong>of</strong> diabetic<br />

rats as compared with the non-diabetic control rats (Table 10).<br />

The findings <strong>of</strong> the present investigation clearly showed the nutritive value,<br />

antimicrobial activity and therapeutic potential <strong>of</strong> the Morinda spp. These<br />

results assume significance as there was no work carried out in India on<br />

Morinda spp. and it is the first report on M. pubescens although its wound<br />

healing activity has already been reported from our lab (Mathivanan et al.,<br />

2006). It is worthwhile to take up further research on different aspects <strong>of</strong><br />

Morinda spp. because it will shed more light on the nutritive and therapeutic<br />

values <strong>of</strong> these species.<br />

References<br />

N. Mathivanan et al. Chemical and biological properties <strong>of</strong> Morinda spp.<br />

Bradford, M.M. 1976. A rapid and sensitive method for quantitation <strong>of</strong><br />

microgram quantities <strong>of</strong> proteins utilizing protein-dye binding. Anal. Biochem.<br />

70: 248 – 254.<br />

Hammer, K. A. C. F. Carson, and T. V. Riley. 1996. Susceptibility <strong>of</strong> transient and<br />

commensal skin flora to the essential oil <strong>of</strong> Melaleuca alternifolia (tea tree oil).<br />

Am. J. Infect. Control. 24:186-189

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