Images - Department of Radiology & Biomedical Imaging ...

CARDIAC AND PULMONARY IMAGING
Brett M. Elicker, MD, Chief
Research Directions:
n Cardiac CT angiography (CTA)
• CTA assessment of coronary allograft vasculopathy after
heart transplantation
• Use of cardiac CTA for pre-surgical clearance
• Use of cardiac CTA for definitive emergency room evaluation
of atypical chest pain
• Evaluation of coronary atherosclerosis in patients with HIV
n Cardiac CT
• Evaluation of pulmonary venous anatomy in atrial fibrillation
• Characterization of myocardial ischemic injury by contrastenhanced
MRI and CT
n High-resolution CT
• High-resolution CT diagnosis of lung disease
• Clinical outcomes following negative CT for acute pulmonary
embolism
• Predictors of poor outcome in patients with acute PE diagnosed
by helical CT
n Cardiac MRI
• Use of novel cardiac MRI techniques and computational
modeling for the quantitative assessment of ventricular
performance in congenital heart disease
• Use of multidimensional flow techniques for quantitative
assessment of flow dynamics in congenital heart disease
• MRI to assess cardiac function after repair of tetralogy of
Fallot; correlation with clinical outcomes
• MRI to assess cardiac function in the single ventricle
patient after Fontan palliation; correlation with clinical
outcomes
• Endovascular therapy and hemodynamic assessment using
MRI guidance
Recent Key References:
Hope MD, Dyverfeldt P, Acevedo-Bolton G, Wrenn J, Foster E,
Tseng E, Saloner D. Post-stenotic dilation: Evaluation of ascending
aortic dilation with 4D flow MR imaging. Int J Cardiol. 2011
Sep 8. [Epub]
Hope MD, Hope TA, Crook SE, Ordovas KG, Urbania TH, Alley
MT, Higgins CB. 4D flow CMR in assessment of valve-related
ascending aortic disease. JACC Cardiovasc Imaging. 2011
Jul;4(7):781-7.
Lee JS, Ryu JH, Elicker BM, Lydell CP, Jones KD, Wolters PJ, King
Jr TE, Collard HR. Gastroesophageal Reflux Therapy is Associated
with Longer Survival in Idiopathic Pulmonary Fibrosis. Am
J Respir Crit Care Med. 2011 Jun 23. [Epub]
Muzzarelli S, Ordovas KG, Cannavale G, Meadows AK, Higgins
CB.Tetralogy of Fallot: impact of the excursion of the interventricular
septum on left ventricular systolic function and fibrosis
after surgical repair. Radiology. 2011 May;259(2):375-83.
Muzzarelli S, Ordovas KG, Cannavale G, Naeger D, Michaels
AD, Higgins CB. Potential of Delayed Gadolinium Enhancement
Magnetic Resonance Imaging for Quantification of Reverse
Remodeling of the Peri-Infarct Zone in Patients With Ischemic
Cardiomyopathy Treated With Chronic Vasodilator Therapy:
Initial Experience. J Thorac Imaging. 2011 May 5. [Epub]
CARDIOVASCULAR IMAGING
RESEARCH INTEREST GROUP
Karen Ordovás, MD, Co-Director
David Saloner, PhD, Co-Director
The overall vision of the Cardiovascular Imaging RIG is to serve
as a world leader in providing early diagnosis and improved
outcomes for patients suffering from cardiovascular diseases.
The CVRIG will develop evolving imaging technologies and
apply currently used imaging methods to determine the etiology
of cardiovascular conditions and to provide early diagnosis
of cardiovascular diseases, with the ultimate goal of reducing
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