Noviembre-Diciembre
156_v40n6(1)
156_v40n6(1)
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550 - Farm Hosp. 2016;40(6):544-568 Ramón Morillo Verdugo et al.<br />
Table 1 (cont.). Bibliographic Review – Pharmaceutical Interventions in HIV+ Patients<br />
Title Authors, year<br />
Type of<br />
study<br />
No. Of<br />
participants<br />
Interventions Objective Time Conclusions<br />
Feasibility and<br />
reliability of<br />
interactive voice<br />
response assessment<br />
of HIV medication<br />
adherence: research<br />
and clinical<br />
implications.<br />
Hettema JE,<br />
Prospective<br />
et al. 2012 24<br />
63 patients<br />
Participants should<br />
communicate their daily<br />
adherence during 2 weeks<br />
in the voice system. The<br />
feasibility of the system<br />
was analyzed and,<br />
retrospectively, compared<br />
with the self-reported<br />
adherence data obtained<br />
during previous follow-up.<br />
A pilot study intended<br />
to assess the feasibility<br />
and reliability of an<br />
Interactive Voice<br />
Response System (IVR)<br />
for assessing treatment<br />
adherence.<br />
1 month<br />
The feasibility of these new<br />
promising systems should be<br />
improved. Besides, further<br />
studies should be conducted<br />
with another comparator<br />
for adherence measurement<br />
which is more adequate and<br />
representative.<br />
Development and<br />
validation of a<br />
predictive model for<br />
the identification<br />
of HIV-infected<br />
patients with Drug<br />
Related Problems: E.<br />
PREDICTOR<br />
Prospective,<br />
Morillo Verdugo<br />
multicenter,<br />
R, et al. 2012 25 open.<br />
733 patients<br />
Periodic<br />
pharmacotherapeutical<br />
follow-up in the PhC<br />
consultations at the<br />
Pharmacy Units in the<br />
hospitals included.<br />
To develop and validate<br />
a predictive model for<br />
detecting drug related<br />
problems (DRPs) in HIV<br />
patients on antiretroviral<br />
treatment.<br />
4 months<br />
The model developed<br />
and validated allows the<br />
detection of those patients<br />
on antiretroviral treatment<br />
at higher risk of developing<br />
a DRP.<br />
Impact of HIVspecialized<br />
pharmacies on<br />
adherence and<br />
persistence with<br />
antiretroviral therapy.<br />
Retrospective,<br />
comparative<br />
Murphy P, et al.<br />
study of<br />
2012 26 healthcare<br />
intervention<br />
7064 patients<br />
Review of medication,<br />
evaluation of adherence,<br />
ease in drug access and<br />
improvement in their<br />
availability.<br />
To assess and compare<br />
the adherence and<br />
persistence with ART by<br />
patients who use HIVspecialized<br />
pharmacies<br />
vs. traditional<br />
pharmacies.<br />
12<br />
months<br />
HIV-specialized community<br />
pharmacies can be effective<br />
means to help patients<br />
achieve a better adherence<br />
and persistence with ART.<br />
Pharmacists’<br />
strategies for<br />
promoting<br />
medication<br />
adherence among<br />
patients with HIV.<br />
Qualitative,<br />
Kibicho J, et al.<br />
multicenter,<br />
2011 27 descriptive.<br />
19<br />
Pharmacists<br />
Semi-structured interview to<br />
participants.<br />
To document the<br />
experience of<br />
pharmacists and provide<br />
a perspective about<br />
adherence barriers<br />
for HIV patients and<br />
describe the strategies<br />
to improve it.<br />
2 months<br />
Further research is required<br />
on the efficacy and costefficacy<br />
of interventions<br />
by Pharmacists in clinical<br />
practice, with the aim<br />
to reach a consensus on<br />
reimbursement policies.