Noviembre-Diciembre

Development of a taxonomy for pharmaceutical interventions… Farm Hosp. 2016;40(6):544-568 - 551
Table 1 (cont.). Bibliographic Review – Pharmaceutical Interventions in HIV+ Patients
Title Authors, year
Type of
study
No. Of
participants
Interventions Objective Time Conclusions
Using different
calculations of
pharmacy refill
adherence to predict
virological failure
among HIV-infected
patients.
Boer IM, et al.
______ 201 patients
2010 28
The adherence calculation
was analyzed through data
provided by the pharmacies
where patients collected
their medication. Assessing
the surplus medication and
the interruptions to the
treatment prescribed.
To analyze the feasibility
of data collection in
pharmacies. To analyze
the impact of surplus
medication and time of
treatment prescribed on
adherence calculation.
12
months
It is important for those
studies using this method
of adherence measurement
to consider the surplus
medication.
Improving adherence
and clinical
outcomes through
an HIV pharmacist’s
interventions.
Ma A, Retrospective 75 patients
2010 29
Optimizing the new
antiretroviral regimens
in order to improve
immunological response
and reduce adverse effects
to the minimum, as well
as improving adherence by
reducing the number of pills
and/or the dosing frequency.
To research the clinical
outcomes of a clinical
pharmacist in the
Kaiser Permanente
Program, based on the
experience with drugs,
in order to provide
recommendations for
change in antiretroviral
regimen.
24
months
Clinical pharmacists can play
a major role in optimizing
adherence and improving the
clinical outcomes of patients.
Assessment of a
Pharmaceutical Care
Program to improve
adherence to
antiretroviral therapy
Codina C,
et al.
observational,
prospective.
2004 28 Multicenter,
541 patients
Previous basal visit and 4
visits every three months.
Adherence estimation is
based on pill count. An
adherence ≥ 95% was
considered adequate (at two
timepoints).
To determine the impact
of a Pharmaceutical
Care Program on
the improvement of
adherence to ART
treatment and the viroimmunological
status of
the patient.
12
months
Confirmation of the
need to incorporate
pharmacotherapeutical
follow-up programs
for patients on active
antiretroviral treatment, in
order to optimize benefits.
Pharmaceutical care
for HIV patients on
directly observed
therapy.
Prospective
Foisy MM, healthcare
2014 30 intervention
study
57 patients
DRP identification and
management, counselling
to physicians in terms of
selection of initial therapies
and rescue regimens for
patients with therapeutic
failure, advice on medication
for patients, clinical
interview with patients,
direct observation of
treatment follow-up and lab
parameters and adherence.
To describe the
development and
provision of a
pharmaceutical care
program for patients
with directly observed
therapy (DOT), as well
as detection of drugrelated
problems (DRPs)
and their respective
outcomes.
14
months
In PhC for HIV patients with
DOT, the Pharmacist offered
a significant contribution to
the initial selection, followup
and DRP management
during antiretroviral
treatment. Besides, they can
help in the promotion of
patient adherence, and in
the improvement in health
outcomes.