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Akademischer Bericht 2005 - Geburtshilfe - UniversitätsSpital Zürich

Akademischer Bericht 2005 - Geburtshilfe - UniversitätsSpital Zürich

Akademischer Bericht 2005 - Geburtshilfe - UniversitätsSpital Zürich

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whether this imbalance is an acute adaptation to the intrauterine environment or whether this imbalance<br />

is due to persistent changes in the sympathicus/vagus system, which could then be transported into juvenile<br />

and adult life with the consequence of elevated blood pressure and higher rates of hypertension,<br />

coronary heart disease, atherosclerosis and metabolic changes later in life It is the aim of this study to<br />

evaluate whether the dysbalance of the sympathicus/vagus-systems in growth retarded fetuses persists<br />

into newborn life, when the environment and nutrition of the newborn is adequate.<br />

01.01.2004-31.05.<strong>2005</strong><br />

Professur/Forschungsbereich: Zisch, Andreas<br />

Multimodality imaging of the female pelvic floor<br />

Aim: Evaluation of the female pelvic floor using volumesonography and MRI<br />

Methods: Patients having an MRI for pelvic floor assessment were also evaluated with volume sonography.<br />

Pelvic floor morphology is evaluated in a multimodality approach in the same volume image.<br />

Outcome variables: Depiction of anal spincter and paravaginal support in the various modes. Volumometry<br />

of anatomical structures (anal sphincter, urethra, levator) and comparison of estimates in various<br />

modes.<br />

01.03.2002-31.12.<strong>2005</strong><br />

Professur/Forschungsbereich: Zisch, Andreas<br />

Multiple courses of antenatal corticosteroids for preterm birth study (MACS)<br />

To proof safety and efficacy of multiple antenatal doses of corticosteroids versus one single dose for<br />

fetal lung maturation<br />

01.03.2004-31.12.2006<br />

Professur/Forschungsbereich: Zisch, Andreas<br />

Nifedipine pharmacokinetics<br />

01.03.<strong>2005</strong>-31.05.2006<br />

Professur/Forschungsbereich: Zisch, Andreas<br />

Nuchal cord entanglements in term and post-term deliveries – Necessity for sonographic assessment<br />

–<br />

Objective: The impact of nuchal cord entanglements on perinatal features at delivery Design: Systematic<br />

retrospective analysis of computerised data Population: 11748 women with planned vaginal deliveries<br />

including 9574 term and 2174 post-term deliveries Methods: Data are obtained from our perinatal database<br />

Perinat 3 between 1995 and 2004. All singleton, vertex, term and post-term pregnancies with<br />

planned vaginal delivery are analyzed after exclusion of incomplete or unreliable data. Main outcome<br />

measures: Intrapartum events, clinical peripartal management, mode of delivery and neonatal outcome<br />

01.03.2004-30.04.<strong>2005</strong><br />

Professur/Forschungsbereich: Zisch, Andreas<br />

Nuchal cords in term and postterm deliveries - do we need to know<br />

Objective: To analyze the effect of nuchal cords on perinatal<br />

features at delivery of term and postterm pregnancies.<br />

Methods: A total of 11,748 women with planned vaginal<br />

deliveries, including 9,574 term and 2,174 postterm deliveries,<br />

were analyzed for intrapartum events, clinical peripartum<br />

management, mode of delivery, and neonatal outcome. The<br />

presence of nuchal cords was diagnosed clinically at the time<br />

of delivery. Data were obtained from our perinatal database<br />

between 1995 and 2004 for retrospective analysis.<br />

Results: The incidence of nuchal cords in term and postterm<br />

deliveries was 33.7% and 35.1%, respectively. Multiple nuchal<br />

cords were present in 5.8% of term and 5.5% of postterm<br />

deliveries. Intrapartum signs of fetal compromise were increased<br />

in all groups, albeit not all reaching statistical significance<br />

Klinik für <strong>Geburtshilfe</strong><br />

<strong>Akademischer</strong> <strong>Bericht</strong> <strong>2005</strong><br />

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