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Sleep Disorders and Sleep Deprivation: An Unmet Public

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<strong>Sleep</strong> <strong>Disorders</strong> <strong>and</strong> <strong>Sleep</strong> <strong>Deprivation</strong>: <strong>An</strong> <strong>Unmet</strong> <strong>Public</strong> Health Problem<br />

http://www.nap.edu/catalog/11617.html<br />

224 SLEEP DISORDERS AND SLEEP DEPRIVATION<br />

using a careful history; lung function tests are used to gauge disease severity<br />

<strong>and</strong> treatment responses <strong>and</strong> sometimes to help differentiate asthma from<br />

other respiratory conditions. The issues that plague equipment development<br />

<strong>and</strong> laboratory access in the sleep laboratory have not impeded the<br />

development of lung function laboratories. Rather, the development <strong>and</strong><br />

accreditation of lung function laboratories <strong>and</strong> lung function equipment<br />

(including portable spirometers) are based on collecting reproducible data<br />

that meet physiological criteria for accuracy, independent of the role of<br />

such equipment as tools evaluated on their ability to independently classify<br />

disease status. It is recognized that the latter requires consideration of multiple<br />

factors, including symptoms, level of impairment, response to allergic<br />

<strong>and</strong> irritant triggers, <strong>and</strong> often empiric responses to therapeutic trials.<br />

Other challenges relate to designing studies that specifically address<br />

a number of distinct potential applications of portable sleep monitoring.<br />

These include screening—which is often population-based, <strong>and</strong><br />

intended to detect cases independent of symptoms; clinical case definition—<br />

identification of cases among patients referred because of health concerns;<br />

disease management in which sleep monitoring provides quantitative data<br />

on progression or regression of disease severity; <strong>and</strong> epidemiological studies—in<br />

which sleep monitoring is used to provide a quantitative assessment<br />

of a physiological exposure or outcome. It is important that any given<br />

evaluation study of new technologies be designed to address a specific question<br />

or related series of questions.<br />

Scoring <strong>and</strong> Processing of <strong>Sleep</strong> Studies<br />

Current scoring approaches use a system of epoch by epoch scoring (30<br />

seconds per epoch) developed over 40 years ago when polysomnography used<br />

only paper-based systems based on analog data. This approach is recognized<br />

to be both labor-intensive <strong>and</strong> time-consuming. Further, reliance on human<br />

scorers using visual pattern recognition requires intensive <strong>and</strong> ongoing training<br />

to achieve high reliability (Whitney et al., 1998), which may be lower<br />

than that potentially attained by automated methods (which also have their<br />

limitations). Visual scoring also may not maximally utilize the spectral components<br />

of the electrophysiological data, which may provide useful information<br />

on sleep architecture. Furthermore, there is a shortage of trained sleep<br />

technicians. Currently there are only 2,198 certified technicians to monitor<br />

<strong>and</strong> score sleep tests, far below the need (Association of Polysomnographic<br />

Technologists, 1999). Recognizing these issues, the AASM convened a task<br />

force in 2004 to reassess current scoring approaches, critically evaluate both<br />

sensors <strong>and</strong> scoring algorithms, <strong>and</strong> update scoring approaches as appropriate<br />

to include digital analysis of electrophysiological data. This report, scheduled<br />

Copyright © National Academy of Sciences. All rights reserved.

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