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Sleep Disorders and Sleep Deprivation: An Unmet Public

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<strong>Sleep</strong> <strong>Disorders</strong> <strong>and</strong> <strong>Sleep</strong> <strong>Deprivation</strong>: <strong>An</strong> <strong>Unmet</strong> <strong>Public</strong> Health Problem<br />

http://www.nap.edu/catalog/11617.html<br />

BOLSTERING SOMNOLOGY RESEARCH 269<br />

Human Development. The NCMRR supports research on enhancing the<br />

functioning of people with disabilities in daily life. Compared to the 1 RFA<br />

established by the NCSDR in fiscal year 2004, the NCMRR established 6<br />

RFAs <strong>and</strong> 4 PAs. Further, between 2001 <strong>and</strong> 2004 the NCMRR established<br />

20 RFAs, while the NCSDR established only 4 RFAs. It is unclear why<br />

there is such a dramatic difference in the activity of these two centers.<br />

Protocol for Research Project Grant <strong>An</strong>alysis<br />

This committee performed a detailed analysis of the 1995 <strong>and</strong> 2004<br />

portfolios of NIH somnology <strong>and</strong> sleep disorders research project grants<br />

(R01) to determine the current investment in the field <strong>and</strong> to examine how<br />

the grant portfolio has changed over the last 10 years. To do so, abstracts of<br />

all sleep-related R01s in the Computer Retrieval of Information on Scientific<br />

Projects (CRISP) database were analyzed. This database collects information<br />

on the number of federally funded biomedical research projects.<br />

<strong>Sleep</strong>-related R01s were collected by searching the CRISP database for all<br />

abstracts that were classified under the following thesaurus terms: insomnia,<br />

periodic limb movement disorder, restless legs syndrome, circadian<br />

rhythm, SIDS, sleep disorder, narcolepsy, sleep apnea, sleep, hibernation,<br />

<strong>and</strong> dream. To limit the number of grants that were not relevant to somnology<br />

or sleep disorders, the committee only included grants in which the key<br />

words appeared in both the thesaurus terms <strong>and</strong> abstract <strong>and</strong> not the<br />

abstract alone. It should be noted that the following conclusions are based<br />

on the number of grants awarded in each area. The committee did not have<br />

access to the applications that were submitted <strong>and</strong> not funded; therefore, it<br />

is not possible to conclusively determine if changes in investment are the<br />

result of NIH policy, the number <strong>and</strong>/or quality of submissions in each<br />

area, composition of grant review committees, or a combination of these<br />

factors.<br />

General Findings<br />

The CRISP search identified 156 sleep-related grants for 1995 <strong>and</strong> 397<br />

for 2004. Upon review of their abstracts a number of these were determined<br />

to be unrelated to sleep. This resulted in 116 total sleep-related grants in<br />

1995 <strong>and</strong> 331 sleep-related grants in 2004, a 2.85 fold increase (Table 8-3).<br />

The number of the grants deemed not relevant to sleep-related research—<br />

34 out of 156 in 1995, <strong>and</strong> 59 out of 397 in 2004—represents a relatively<br />

constant percentage (i.e., 21 percent <strong>and</strong> 15 percent, respectively; supplemental<br />

grants <strong>and</strong> grants with no abstract were also not classified). Thus,<br />

use of this methodology to track temporal trends in number of grants seems<br />

appropriate. Of the relevant sleep R01 grants there were 253 principal<br />

Copyright © National Academy of Sciences. All rights reserved.

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