~-.~JiVIi~ s«M .

-17-
wrm meraxd cc nm-s*rJCe .-s . '1=e rate ~ only 101 iug :rr `or tMee
sarried to a $m*er of eure than 20 cioa :ecte pes day . :a~
oadoudinq variables `wre taken into acodmt laqe, rac¢, edumtim,
reyidence and ry,ysbands• oxtqmt .ion), the eaRSS risk vas 371 and e1,
rewectively . Noix of tlrx findings .ere atatistically significant .
lk~ . the resolts have to be interpreted with great cautior. because
the rt¢y w never desiqned to ebenin infon :~on an lmaive smKuq .
PqrtBecaore, rhaceuer sedrinq intomnttan res aaailablc carespaded
o :ly to the exposure at tfine of earollsent into the sttdy .
Li6st and wynder 1311 assessed e:@aaite to seoxHa_'y s:mke in a
suMet of :v :,kirA patients included in a large sody of tabscm-
related cancers . Oot af 2S sade rases six reportd esposure to ocher
pecple's aol:e at hone . as mpseed to 5 oit of 25 oarczoln . lYqrmn
e( ttssse eases nWSted eRasufe at work verss 1l of the aurcrolsS this last ditfezence wws barely statisrlcally siynificsait . Aasq tne
feale g.aq (m'S3) abaR the saee Ittapurtion of eeses and cmtrols
were e :preed to oHrt pecple's >odee at hal ad wctc : omsequertli
the association with lunq Cancer w nac .seatiaeially siqnificant .
Sandler, et . a1 . reportad tlr, results of a casreantzol study
ia•nl-rLq Sle r~r pa'ierKs (all sites, eaotpt basal-cell rancxr of
the slcin) and SIB controls . in three separate publiatiars the au.hers
assessed t .he association l:etwee~ tt:ese crrxrs aid : 1) emcsure in
clutdnaod and adult life to the ssokinq of all !coselwld nedtrs ut:o
smked (351, 3/ early lift fte to parental sadci .•i9 (36l, aM
31 e:qasure in adaldnod as a resolt of spnuse's saok:ag 1371 . in the
: :at of t.tiese --'e odi• ratio for t .Sae e,-csed to one s-nvr
http://legacy.library.ucsf.edu/tid/dsk94c00/pdf
-LS-
in the houxhold ees fomd to Ce 1 .5. If e:¢oswd to the moke of tuo
indivi.luals, the oQls ratio inaewted to 2 .3 . and to 2 .6 if ex;ioeed to
the snoke p[od:nad by three s:mkers . Tfiis tred was statisticalll•
significant (p < 0.01) . Ba..ecar . it Mould be noted ttut an in¢ease
in [isk walan uEsetv.d for active avokers .to pad been espoaed to
the svdce of otts!rs in the Aasetold .
11e overall unosr risk for all swdy subjects (passi.e . as rell
as active, smokets) Ws reported to be elevated in both of two
circwetaz,oes : .i+ei expoaure to setvNary sadmd had ocvrref dorinq
d:ildamd miy IOnal .61 . and ,Aen the emilmMifte took place in adult
life eslu.iuely (OIal .51 . for an individual espased in both pericds
of life, the odds ratio exceadad tvo 10R-7 .7) .
• Ibr the seoond repo