~-.~JiVIi~ s«M .

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e.eimn:es for achPr levela u[ a4aw[e, t~ also mm foiad to siw a
doee-respmse re ;atlo1uhia. %akiC+ further svppozn the mte for a
ar .5a1 relatians,hip . fbr a so.e.iat ccsparable level of exposure .e
.tre unable to detwct aay significant in¢esse in lmq orcer risk .
Occ point estimte of effar- fQ those individuals married to wakers
of 21-40 ciqarettesJday .na an adds rat .'o of 0 .906 (959 ¢ :
.609-
1 .35) . ~ exposure uss malyred as a atsgrical var~-ahle . For
ntqtur levels of exposure .e fourd risks ahnue the aoll valoe . aut
aa. .• ttese fiidiags were aot statiatiolly signifia,t . '_M analysis
of exposure data as a apRi : .cus variable w mnsistant with the
ahoee -m .ultss inleed the effect twrl fQ a differential of exposure
of 20 e[9arerves per day rs hstely abave t1r iuil value (OR • 1 .01I),
with c+anfidenee limits that include sueh a fiqure- !mr tMre w aay
evlderaae of a liroar trend .
9hiL report is ent tin anly a,r that has bssn unsble to onnfism a
statistically signiffont as.nefatLon htsn nu~er of cigarettes
.ukad by the spase od lnq anoer risks . Akie., at . a1 .(32)
reported an adds ratio of 1 .31 (909 O., 0.M-3 .171 far LSare .,paseA
to spsoe mekleq aS 20-40 ciqeratees/day (reported as 140-279
ciqarattes/umk) . fbr a s.fnllar leral of eaposure, hlaqer at . al .
(331 found an adds ratio of : .3 (95% CLs 0 .8-2.7) . 8rse latter
estisatae . alrlooqA not signifiwnt, are within the r+b'qe of the
suspeetd mbqniCAe of effact . A closer fi9ure to as re .ulta,
haever . w reported by Garfinlml in his aeslysia of the 7aerinn
Canoer Sndety Stuly daa 124) . far eiFa.ure to epouse seaking of
20 or :rore ctgattres.Iday he fmad an o00s ratio of 1 .10 . Sisilarly
his results aeje aot uqnifiwM .
5V£GZS909Z
http://legacy.library.ucsf.edu/tid/dsk94c00/pdf
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Oor results regarding tt~ .uvariable emuct be aommted for by
the fi,alusiae of faoer senkarn sina aay effect due to this
eirametnr.e wuid aC_ in th opgasite .tire+ . . . ., . that is, would
inflate the risk attriLutabla to ama.uce. Nor asn it be esplained Dy
the use of snsopte lnter.ie.e either, sime eo siep+ifiant
diffetaKa.s ware faund Eet.e.n tle rtLetes fow the latter aM the
eatiwtas for s.lf-resputls¢a . 'Ru eHsct aaold ntt haw he.n diluted
by the irclusSon of mmles . siroe they sees to ahher a siadlar ruponw
to that of w.n . Finally . m .qaal dirtrfla>`. .bon In ews aid ceattreta
ragenSi,g om!ounlkg variablas ennt 6a raspayiDle far the
fiediags . as *q)est.d by the airor dfnqe the estimstes mdecgo M>n
those veriabla ara ineloded in the airlyefs .
11a did aat find an effect depn0.¢ ae the d urar.tm of exposure
to passiva smki:g a s sass¢ed by the an6es of ysan the sppse
smalord rlSle .uri.0 ud livin9 mqetMr . i wo other studies Ird
evaluated the effect attriEutable to this srbuie of aposors .
Oalager at. al . (33) tepoctad ern slyelffaat ferrsw in risk d ue to
s{uee simtdnq of 1-20 years (al - 1 .73, 9S1 Q.: .52-S .s2) . 21-30
years Ipt - 1 .7l . 951 CW .60-5 .101, ud 930 yaaf ( 08 • 1 .24, 951
0. : ./2-3 .531 . T1rae figures did nat slnr avidrr.y of a linrr trand .
AkiLS . at . al . 132) reported od+ , rstioe of 2 .1 1991 C1s 1 .0 - 4 .31
for tim .e a arrid to sndzrs of 1-19 ya.rs, of 1 .5 1909 as 0 .8 - 2 .71
for those e,ptns0 during 20-39 years . ad an odds ratio of 1 .3 1901
0.: 0 .7 - 2 .51 for thcse eaposed to 40 or aore years . Strtse em
s(9nificaot effetn did ,nt shw evlds,ee of a Unat trend .
6arfi+Gce :, at, al incorporated a different meenue of dtsetian of