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M<br />
ostegoraes .<br />
-51-<br />
At tus point it xas Also oanidere.i pe^anent to look at<br />
estineres for spaafie stratn of the studY FWulation<br />
.<br />
Peviaus<br />
srydin have sqgested that the effe¢ of psssive aukitg ney vary<br />
pet.een the acxs, or by type of interview or acosd£rvl to imu kiaq<br />
R; stor) .<br />
The ewtched design wald nat allo+ :zs to obtain estizetee<br />
for the zrin effects of such variables Iby desiqn .Aoee effects heve<br />
been set to be zerol . but eseintes for eacA of their leuels could<br />
provide useful ]nfornet:on oe the relatianhiP beneen the risk factor<br />
and the sady disease. Also, previoux -reseazch wrk has suq'lesrcd<br />
that passive saokinq soy daewmane the type of histoloqic twor<br />
.dereloceC by the pstiena . ltrreforew re wntd to see if the<br />
mqnitode or dizectioe of the effect varied aocudinq to the<br />
histnlagic type --mmside:-A .<br />
folla .s .<br />
Lf xrmwty, tie sOeA takel at tnis .raqe of tLe anslysis uere q<br />
1) A logistic eodel w fitted for each of the e>qxrsute<br />
variables . Tfine nodels p.wided escisntess of effect for the<br />
noosere in question, takLq into aQVm all 439 psira available<br />
for analysis .<br />
2) 5 loqiseac model uss f1etM for eaU of t .he ezcosue variables<br />
ard tleit interacclm with the nciahle TYPE af IICtP.V[fl+. l~<br />
ttese sodels es•..tsetes for effects wcre aMaind for Sf7.F-<br />
P15FQOfMfS and for SRIPACATE Pf57ONOfMfS .<br />
http://legacy.library.ucsf.edu/tid/dsk94c00/pdf<br />
3) A lapistie moiel .as fitted for exh of the<br />
emesure variables<br />
a.d thear i .» ... .e :oa vac : the vzzriable 4-ORZtL IQS.qtY. fY®<br />
these sodels senaraee est'ua ;rs .ere vlny ne d for<br />
t2VFA 3t/67B<br />
and Fvp{R sqlRpS .<br />
41 A Ioqistic raWel w fitted for . ech<br />
o f th e p___ variables<br />
and Ltiz i n2eraeeiama vith the variabl e<br />
umvided eatiewtes for F}f1A16 Md 17A= .<br />
g7c. T.eae mQ3els<br />
51 A laqietic arfel .as fitted for e .ch of the exposu¢e veriablas<br />
ard tAeir lntsssctions . .ith the varzable lR811II=e 1-!PC .<br />
FY?zrate effects WRre obtwlned for FpmfAlpID A!O 2Vyl . (la<br />
CMBqflNA aed 11DII{701AGTm At0 f71HERS .<br />
6) 'hsts of the siqnifian :.e of the effeRS of all of the ivNe<br />
PU'a"eterS Kra obralned . as weil as tests of the siqnifiau,,, uf<br />
the iotsscc;oas . 4he lattei are atIuivalait to testinq the null<br />
hYPotheis tnst the effect doea eot vary aa=yiry to the leuels<br />
of the st-Zatifyinq varf.zDle .<br />
)1 wre eaplex epdels iaelud'vg the eqOaure variable in<br />
questian aid tio . t.Rree aM four u.o-yy interactions .ere<br />
fitted .<br />
91 Models with L~le +r~ vanaqla attl all the hASible<br />
m~binatiau of Mrer .aY ieterectiqys .ete fittod .
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