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In<br />

wdiffereneiatai ^el1 typn .<br />

A msa c ;e.•rc assacia[_on ' s fou:d bero,eer: hl.stn!oqic :ype and<br />

gpX . MG6t studie9 a9tCe thet epideifrcld rfl'^llYllla is TJCe frequOR lf1<br />

ma!es tlw+ finela<br />

. 7fie pivporcim of male raxs classified as<br />

epideeroid earci+nies nn9as Ue*.ween 381 qu1 64" wr fe :mles, the<br />

val :xs are 6etweeA 21% end. 551 . 1Ye ottrt notabie dSfel~- occ.as<br />

an,,4 ademurc~mies : this taor is e=h so:e mnm : evrrwl .aien tlw,<br />

nm . ap to 52% of a11 1 :m9 earner casa in faftles have bem repa'tc1<br />

to `slong to these qraip, M~ 331 is the highest aavo9 aen to be<br />

pces,ced in recent studia .<br />

17w differenm in tmeki+sl eabits Cet .een seA and .omen aulgeses<br />

dre such iubits s .y 6e raspotnlDls for the diffeZms.a in histoloqic<br />

types avq the .esu . Oefortontaly . this has net been pmperly<br />

assesasd in any at•* . Nast reperts deal with the sex-hinnlegic<br />

type, or the s+okilK''l3tolegie type .a.otiariam. 2ne thier+ey<br />

interacrlon, xx-sdcUq-histoloqie type, reawins to be studied .<br />

http://legacy.library.ucsf.edu/tid/dsk94c00/pdf<br />

. aGPIfR W4D<br />

In Anrii of 1982 the Ner York State ptpattmeot of Health<br />

initiated a latqe stidy nf the tpldaefolary ot luq oen'i . t!w York<br />

SGt., with appmximstely 10 .000 oses of Wnq caneri reprsted every<br />

}rar to its tumr registry, ptovided an e>mellerc setting for a stufy<br />

of this natore . The pmject wes intaided to be emprelx•naive, that<br />

is . to intiode both snokinq and nat-smdcLq long caneer cases . Stsdy<br />

of the q[oup of sndcing cases wes limttad to the clinidl ard<br />

patAolo9inl cfur .c.e.istics of lunq canner, .heress the asses>fne :t of<br />

espnsure to passive sndciig ad other relevsnt em .im.rntal variables<br />

w:re the mein study variables in the non-s:rqking The ruay<br />

design also d1iaC for a population based mse,rtdrd emtrol groop<br />

(this gM'P wil l be descihed Iater in full dereil l . Lt is only clese<br />

~ lattel qn .xps - sm-aiokinq cases and their wtteapordvnt<br />

Mtdrd ceetrols - that will be used to assess the effect of<br />

eW:sure to paesive srokinq on t,rye risks of lJry caKer . 1Te<br />

-30

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