~-.~JiVIi~ s«M .

-21-
to 100 nq'of tmt substence lato the air 1461 .
91t ho
.w mrll mq,•' to these subetnnK¢s doel the reqular mr
smokiry perfa : really erpesierm? This has beP+. arsy difficcvlt tn
qrwn•Sfy . 'O+e oooartSations of tmacm oouponr+rzs in t.he emuanat
tepet.is oe rnveran faccees
. The aeumt of tobaao camaxd, the
valune of aebieot air, the size of the :oom iArre swkin7 takes place .
aM the type and aeamt of veiLlatien in an rnclosed space are soie
of the aerl variables that affect sodce intake . Dr prWinity Of the
passive sariter to the swtoe of sabks aed his/her pattam of
iMalarian ery alan affect attu .l e«pes.ue 4491 . siailarly . the
amkiig patterv of the individuls Mn do tire smkinl need to be
oon"dared
. lyr i••••••••••, the vatiatios in poff frequeoc,v . putff
duatton and puff volwe an knwn to affer borh tre dmmiwl
oompaaitian of sidestraem 4oke and its bioloqiwl activity (S0-sa) .
Even the srtoker "s health statos sam to affect the wwy in
.Mich
sidestesa ssake is ptoLOed (55) . In faet, it is the sidest:eam
senke that has bsw sydl[led by tta above ard uttrs factors t .hat
oanrtitote t.1n ree! .MQonns to the pessive asdcer . Sane autlars
prefer to refer to this as emiromatthl tobscoo sdoe raUer Uwl
s :jestleam smke .
Desoite these diftlcoltin
. sae stuCies have attenxed to
quentify actual ecgosure by mesrain9 tohaRo aetabolites in had!v
produ«s . 5er,p
:byacianate ard mtinine are found in the blood,
ur~, ' senm and saliva of the passive seoker (4S . 56-60) . Ntl+oqh
iiycriarote msy molt ![an otl+er sourre - i .e . leafy veqetables -
http://legacy.library.ucsf.edu/tid/dsk94c00/pdf
_2=_
caunsne is a specific aerker far eeposure to tmecnv mwke nnd
therefore its preseoce in the nomaQOkeis is ta .er- as evidrnte of
pi+sive imela•ion . In one esq,eriment a researcher ves also able to
identify nKegenic wlsunoes in the orine Of aocje~zs eiposed to
swke in a prxaly ventSlatai rooA (60/ .
6tudies aieed at deterasininq the apecifie de(asition of
envi . ... .. .. . .~ snehe ceqponmU in the lurq tissues are very sr.anty .
In tlr.my . the biotogiosl feetaes of the aurtary aM pAysyoioqy of
the huaen reapiratay systm . ud the physiml and tlamiol
cMracreristio Of slEestsese yoke, nqgest th+t sarL deposition
takes place . The este0t of it . hv+eaer, has bxn a ratter of debete .
oi_ferent aotlsas hsve remeted high levels of mdre bronrhial
depositicn ranging Ira 116 (61-62) to 606 (63) .
ConvrrselYr peli .ce aM Lorty (66) think that pt passiw
s^uYers an espnsad to a m4dw1 asant of asoke . peth.ps m .~. than
the qoivalerc Of aee ciqarette per day . It has been us)qested that
a" en erpccure oonveys a negliqi6le risk /651 . Mith respect to
aLLs, it slwld be sord tlrt tq treYnld level Of asposice fer the
develouent Of lisg runoer has Eeen established . Therefon, any le~el
of .xPoaire - incloSfeq the low leval attsirs.d by psasi.e snyLiip -
slnuld be oostiderd pota+txally able to elicit a qreirvlenic
rest.rrse .
Another s.ties Of studies have been aired to dete .t the .f•.eccs
of pessive seqkyq in the respiratyy •uKtioo of pusive sekers .
'M1is la particularlY relevant since saae aotlrns tbink -h .t an