Nuclear Medicine Research topic(s) - Universitäts KrebsCentrum ...

Nuclear Medicine
Research topic(s):
Characterization of tumor metabolism and properties by means of PET tracers with emphasis
on radiation therapy related changes.
Group leader(s):
Prof. Dr. med. Jörg Kotzerke
Department of Nuclear Medicine
Medicial Faculty Carl Gustav Carus
Technische Universität Dresden
01307 Dresden
Ph: +49-351-458 4160
Fax: +49-351-458 5347
E-mail: Joerg.Kotzerke@mailbox.tu-dresden.de
Education:
1977-1983 Hannover Medical School, Germany
1983 Diploma (Medicine), Hannover Medical School, Germany
1985 MD with Prof. Dr. Heinz Hundeshagen, Hannover Medical School,
Germany (Dr. med.)
1991 Venia legendi (Nuclear Medicine) and academic degree (Dr. med.
habil.), Hannover Medical School, Germany
Training:
1984-1988 Assistant, Institute of Nuclear Medicine and Biophysics, Hannover
Medical School
1989-1995 Senior consultant, Institute of Nuclear Medicine and Biophysics,
Hannover Medical School, Germany
Clinical Experience:
Tumour diagnosis with PET, radionuclide therapy
Professional Appointments:
1995–2002 Associate Professor of Cardiovascular Nuclear Medicine, Dept. of
Nuclear Medicine, University of Ulm
2002-present Professor of Nuclear Medicine, Universitätsklinikum Carl Gustav Carus,
Technische Universität Dresden, and Medical Leader of Positron
Emission Tomography Center, Research Center Dresden-Rossendorf
Publications: 171 publications in scientific peer-reviewed journals
Funding: by DFG, BMBF, SMWK, Carreras-Stiftung
Journals: Reviewer for Nuklearmedizin, EJNMMI, JNM, Cancer Res, IJRB
Grant review: DFG, Dtsch. Krebshilfe, Cancer Research UK
Societies: DGN, DRG, EANM, SNM, DKG
Group members:
Scientists: Dr. med. Bettina Beuthien-Baumann, Dr. med. Klaus Zöphel,
Prof. Dr. rer. nat. Gerd Wunderlich, Dr. rer. medic. Michael Andreeff, Dr. rer.
medic. Roswitha Runge, Dr. rer. nat. Maria Wendisch
MD students: Dirk Aurich, Maria Hentschel, Stefan Hilliger, Manuel, Popp, Ina Quade,
Sabine Zierold
Internal collaborators:
Michael Baumann, University Cancer Center, Department of Radiation Oncology
Martin Bornhäuser, Department of Internal Medicine I
Nasreddin Abolmaali, OncoRay
Leonie Kunz-Schughart, OncoRay
Jörg van den Hoff, Department of Nuclear Medicine
Heinz Reichmann, Alexander Storch, Department of Neurology
Stand: 29.03.2011

External collaborators:
Sven N. Reske, Dept. of Nuclear Medicine, University of Ulm, Germany
Geerd Meyer, Dept. of Nuclear Medicine, Hannover Medical School, Germany
Frans Corstens, Dept. of Nuclear Medicine, University Hospital Nijmegen, The Netherlands
Rodney Hicks, Inst. of Molecular Imaging, Peter MacCallum Cancer Centre, Melbourne,
Australia
Participation in collaborative research projects (local, national, international):
BMBF 03ZIK/OncoRay
EC Fi6R-055785 Biocare
List of most important publications 2005 - 2010:
1. Luboldt W, Volker T, Wiedemann B, Zophel K, Wehrmann U, Koch A, Toussaint T, Abolmaali N,
Middendorp M, Aust D, Kotzerke J, Grunwald F, Vogl TJ, Luboldt HJ (2010). Detection of relevant
colonic neoplasms with PET/CT: promising accuracy with minimal CT dose and a standardised
PET cut-off. Eur Radiol 20, 2274-85.
2. Luboldt W, Zophel K, Wunderlich G, Abramyuk A, Luboldt HJ, Kotzerke J (2010). Visualization of
somatostatin receptors in prostate cancer and its bone metastases with Ga-68-DOTATOC
PET/CT. Mol Imaging Biol 12, 78-84.
3. Hentschel M, Appold S, Schreiber A, Abramyuk A, Abolmaali N, Kotzerke J, Baumann M, Zophel
K (2009). Serial FDG-PET on patients with head and neck cancer: Implications for radiation
therapy. Int J Radiat Biol 85, 796-804.
4. Bruechner K, Bergmann R, Santiago A, Mosch B, Yaromina A, Hessel F, Hofheinz F, van den
Hoff J, Baumann M, Beuthien-Baumann B (2009). Comparison of [(18)F]FDG uptake and
distribution with hypoxia and proliferation in FaDu human squamous cell carcinoma (hSCC)
xenografts after single dose irradiation. Int J Radiat Biol 85, 772-80.
5. Gillham C, Zips D, Ponisch F, Evers C, Enghardt W, Abolmaali N, Zophel K, Appold S, Holscher
T, Steinbach J, Kotzerke J, Herrmann T, Baumann M (2008). Additional PET/CT in week 5-6 of
radiotherapy for patients with stage III non-small cell lung cancer as a means of dose escalation
planning? Radiother Oncol 88, 335-41.
6. Schutze C, Bergmann R, Yaromina A, Hessel F, Kotzerke J, Steinbach J, Baumann M, Beuthien-
Baumann B (2007). Effect of increase of radiation dose on local control relates to pre-treatment
FDG uptake in FaDu tumours in nude mice. Radiother Oncol 83, 311-5.
7. Liepe K, Brogsitter C, Leonhard J, Wunderlich G, Hliscs R, Pinkert J, Folprecht G, Kotzerke J
(2007). Feasibility of high activity rhenium-188-microsphere in hepatic radioembolization. Jpn J
Clin Oncol 37, 942-50.
8. Kotzerke J, Linne C, Meinhardt M, Steinbach J, Wirth M, Baretton G, Abolmaali N, Beuthien-
Baumann B (2007). [1-(11)C]Acetate uptake is not increased in renal cell carcinoma. Eur J Nucl
Med Mol Imaging 34, 884-8.
9. Beuthien-Baumann B, Strumpf A, Zessin J, Bredow J, Kotzerke J (2007). Diagnostic impact of
PET with (18)F-FDG, (18)F-DOPA and 3-O-methyl-6-[ (18)F]fluoro-DOPA in recurrent or
metastatic medullary thyroid carcinoma. Eur J Nucl Med Mol Imaging 34, 1604-1609.
10. Brogsitter C, Pinkert J, Bredow J, Kittner T, Kotzerke J (2005). Enhanced Tumor Uptake in
Neuroendocrine Tumors After Intraarterial Application of 131I-MIBG. J Nucl Med 46, 2112-6.
Stand: 29.03.2011