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Chiropractic 2025:

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<strong>Chiropractic</strong> <strong>2025</strong>: Divergent Futures<br />

integration changes within the central nervous system, but it was unclear whether those changes, whether caused by<br />

correction of vertebral subluxations or an “afferent barrage associated with the adjustive thrust,” 157 were affiliated<br />

with beneficial clinical outcomes.<br />

Research in the scientific exploration of health and healing (which could potentially find overlap with epigenetics<br />

research) can also include the exploration of chiropractic concepts, theories, and principles. For this purpose, the<br />

chiropractic community will need to operationalize and publish key chiropractic concepts such as innate intelligence<br />

and retracing; new tools to detect and measure such forces; and research methods that can test key clinical theories<br />

found in traditional chiropractic principles and philosophy as they apply to health, disease, and healing. From such<br />

operationalized concepts, scientific questions and specific aims can be developed for research that can help develop<br />

new insights and views on contemporary vitalism. A step toward this direction is Life University’s annual Octagon<br />

conference series, which seeks to reconnect chiropractic with the larger field of vitalism—recognizing that most<br />

healing traditions, such as oriental medicine, Ayurveda, and Naturopathic medicine, have similar assumptions, or<br />

principles and clinical theories of their disciplines. These healing traditions also promote research on many aspects<br />

of the body’s self-healing capacity.<br />

Another category of research beyond clinical efficacy and cost effectiveness focuses on epigenetics and the effect of<br />

spinal manipulation on gene regulation. The premise of epigenetics is that the physical environment, combined with<br />

how individuals react to, perceive, and behave within their environment, influences genetic activity. Thus, lifestyle<br />

choices, frequent exercise, and physical care/treatment such as manipulation should influence longer-term genetic<br />

activity. Manipulation influences the balance of inflammatory cytokines (which can amplify or limit inflammation)<br />

and the activity of “molecular chaperones” 158 (sometimes called “chaperone genes” 159 or “chaperone proteins” 160 )<br />

that influence genetic expression by ensuring correct transport or folding of proteins. 161, 162 It has been postulated that<br />

chiropractic care can affect genetic mechanisms by influencing physiological processes that affect DNA repair and<br />

oxidative stress. While several chiropractors question the credibility of the research conducted by Campbell et al., a<br />

2005 article by Campbell et al. found that chiropractic care increased levels of serum thiol, 163 which can provide a<br />

surrogate estimate of DNA repair enzyme activity and human health. Through epigenetics, it has also been posited<br />

that chiropractic care can influence genetic expression by changing a patient’s perception of the environment to<br />

encourage appropriate, constructive responses to environmental changes. 164 Dr. Bruce Lipton posits in “<strong>Chiropractic</strong><br />

Philosophy and the New Science: An Emerging Unity” that immaterial vibrational energy fields and physical<br />

chemicals (i.e., the material, physical, or chemical forces of science that serve as the foundation for the idea of<br />

genetic determinism) can control and coordinate the movement of proteins. Dr. Lipton posits that allopathic medical<br />

philosophy falls short of accepting the importance of the immaterial vibrational energy fields, and that biophysics<br />

research shows that vibrational energy waves can be more effective in signaling protein movements than physical<br />

chemicals, and thus are more significant in “controlling” life. Dr. Lipton credits D.D. Palmer with recognizing this<br />

over a century ago. 165<br />

Drs. Lipton and Weissman further explain that environmental signals (either physical or energetic) cause proteins<br />

to change shape and thus create the functions of life, “Because the majority of us have a perfectly healthy genome<br />

and produce functional proteins, illness in this group can likely be attributed to the nature of the signal. There are<br />

three primary situations in which signals contribute to dysfunction and disease. The first is trauma. If you twist<br />

or misalign your spine and physically impede the transmission of the nervous system’s signals, it may result in a<br />

distortion of the information being exchanged between the brain and the body’s cells, tissues, and organs.” 166<br />

New information on epigenetics has implications for personalized care, where providers could differentiate which<br />

patients would be more likely to respond to adjustments, or if some patients would be predisposed to back pain or<br />

back problems. Combining the research and concepts of epigenetics with those of self-healing and vitalism could<br />

prove a powerful impetus for greater acceptance of chiropractic legitimacy and could help move the field toward<br />

achieving much expanded cultural authority.<br />

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