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ACCEPTED MANUSCRIPT<br />

[224] S.R. Denison, F. Wang, N.A. Becker, B. Schule, N. Kock, L.A. Phillips, C.<br />

Klein, D.I. Smith, Alterations in the common fragile site gene Parkin in<br />

ovarian and other cancers, Oncogene 22 (2003) 8370-8378.<br />

[225] V. Kirkin, D.G. McEwan, I. Novak, I. Dikic, A role for ubiquitin in selective<br />

autophagy, Molecular cell 34 (2009) 259-269.<br />

[226] Y. Kim, J. Park, S. Kim, S. Song, S.K. Kwon, S.H. Lee, T. Kitada, J.M. Kim,<br />

J. Chung, PINK1 controls mitochondrial localization of Parkin through direct<br />

phosphorylation, Biochemical and biophysical research communications 377<br />

(2008) 975-980.<br />

[227] J.W. Um, C. Stichel-Gunkel, H. Lubbert, G. Lee, K.C. Chung, Molecular<br />

interaction between parkin and PINK1 in mammalian neuronal cells,<br />

Molecular and cellular neurosciences 40 (2009) 421-432.<br />

[228] K. Shiba, T. Arai, S. Sato, S. Kubo, Y. Ohba, Y. Mizuno, N. Hattori, Parkin<br />

stabilizes PINK1 through direct interaction, Biochemical and biophysical<br />

research communications 383 (2009) 331-335.<br />

[229] A.J. Whitworth, J.R. Lee, V.M. Ho, R. Flick, R. Chowdhury, G.A.<br />

McQuibban, Rhomboid-7 and HtrA2/Omi act in a common pathway with the<br />

ACCEPTED MANUSCRIPT<br />

Parkinson's disease factors Pink1 and Parkin, Disease models & mechanisms 1<br />

(2008) 168-174; discussion 173.<br />

[230] J. Yun, J.H. Cao, M.W. Dodson, I.E. Clark, P. Kapahi, R.B. Chowdhury, M.<br />

Guo, Loss-of-function analysis suggests that Omi/HtrA2 is not an essential<br />

component of the PINK1/PARKIN pathway in vivo, J Neurosci 28 (2008)<br />

14500-14510.<br />

[231] L.S. Tain, R.B. Chowdhury, R.N. Tao, H. Plun-Favreau, N. Moisoi, L.M.<br />

Martins, J. Downward, A.J. Whitworth, N. Tapon, Drosophila HtrA2 is<br />

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