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ACCEPTED MANUSCRIPT<br />

dispensable for apoptosis but acts downstream of PINK1 independently from<br />

Parkin, Cell death and differentiation (2009).<br />

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M.C. Dekker, F. Squitieri, P. Ibanez, M. Joosse, J.W. van Dongen, N.<br />

Vanacore, J.C. van Swieten, A. Brice, G. Meco, C.M. van Duijn, B.A. Oostra,<br />

P. Heutink, Mutations in the DJ-1 gene associated with autosomal recessive<br />

early-onset parkinsonism, Science (New York, N.Y 299 (2003) 256-259. Epub<br />

2002 Nov 2021.<br />

[233] V. Bonifati, B.A. Oostra, P. Heutink, Linking DJ-1 to neurodegeneration<br />

offers novel insights for understanding the pathogenesis of Parkinson's<br />

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[234] S.J. Lee, S.J. Kim, I.K. Kim, J. Ko, C.S. Jeong, G.H. Kim, C. Park, S.O.<br />

Kang, P.G. Suh, H.S. Lee, S.S. Cha, Crystal structures of human DJ-1 and<br />

Escherichia coli Hsp31, which share an evolutionarily conserved domain, The<br />

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[235] R.H. Kim, P.D. Smith, H. Aleyasin, S. Hayley, M.P. Mount, S. Pownall, A.<br />

ACCEPTED MANUSCRIPT<br />

Wakeham, A.J. You-Ten, S.K. Kalia, P. Horne, D. Westaway, A.M. Lozano,<br />

H. Anisman, D.S. Park, T.W. Mak, Hypersensitivity of DJ-1-deficient mice to<br />

1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress,<br />

Proceedings of the National Academy of Sciences of the United States of<br />

America 102 (2005) 5215-5220.<br />

[236] C. Martinat, S. Shendelman, A. Jonason, T. Leete, M.F. Beal, L. Yang, T.<br />

Floss, A. Abeliovich, Sensitivity to oxidative stress in DJ-1-deficient<br />

dopamine neurons: an ES- derived cell model of primary parkinsonism, PLoS<br />

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