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Unusual Causes of Stroke - Hypercoagulable States and their work-up

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Antiphospholipid Antibodies: A<br />

Conceptual Challenge<br />

• Antiphospholipid antibodies<br />

– Anticardiolipin p ( (aCL) )<br />

– Antibodies to β2 glycoprotein 1 (β2GP1)<br />

– L<strong>up</strong>us p anticoagulant g ( (LA) )<br />

– Others<br />

• These antibodies do not recognize g the same<br />

antigenic epitopes<br />

– Can be found together or independently

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