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Unusual Causes of Stroke - Hypercoagulable States and their work-up

Unusual Causes of Stroke - Hypercoagulable States and their work-up

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Antibody Targets in Antiphospholipid<br />

Antibody Syndrome<br />

• L<strong>up</strong>us anticoagulant<br />

• Cardiolipin(s)<br />

• Beta(2)-glycoprotein 1<br />

• Phosphatidylserine<br />

• Prothrombin<br />

• Activated protein C<br />

• Tissue plasminogen<br />

activator<br />

• Plasmin<br />

• Annexin A2, A5<br />

• Protein Z<br />

• Other platelet <strong>and</strong><br />

endothelial antigens<br />

• And more besides<br />

– Neurons<br />

– Astrocyes y

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