Unusual Causes of Stroke - Hypercoagulable States and their work-up
Unusual Causes of Stroke - Hypercoagulable States and their work-up
Unusual Causes of Stroke - Hypercoagulable States and their work-up
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Catastrophic Antiphospholipid<br />
(Asherton’s) Syndrome<br />
• ~1% <strong>of</strong> cases<br />
• Widespread microvascular thromboses in<br />
the presence <strong>of</strong> antiphospholipid antibodies<br />
• High rate <strong>of</strong> mortality: 30 30-50% 50%<br />
• Considered an indication for<br />
immunos<strong>up</strong>pression<br />
– However, no good controlled trials<br />
– No proven immunos<strong>up</strong>pressive regimen
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