Unusual Causes of Stroke - Hypercoagulable States and their work-up

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Hereditary Abnormalities of Clotting Factors • Association with deep venous thrombophlebitis well established • Significant in cerebral vein / venous sinus thrombosis • Significance in arterial stroke not well established tblihd
Factor V Leiden and Deficiencies of Protein C, Protein S, Antithrombin III • Factor V Leiden – Mutation of factor V – Prevents cleavage of factor V by activated protein C – Present in up to 9% of individuals – Important in venous occlusion • 20% of individuals with initial DVT • 60% of o individuals d v du s with w recurrent ecu e DVT V
Page 1 and 2: Unusual Causes of Stroke John EE. G
Page 3 and 4: TTopics to CCover • Anticardiolip
Page 5 and 6: Anticardiolipin Antibodies: History
Page 7 and 8: Antiphospholipid Antibody Syndrome
Page 9 and 10: Antiphospholipid Antibody Syndrome
Page 11 and 12: Antiphospholipid Antibody Syndromes
Page 13 and 14: Antiphospholipid Antibodies: A Conc
Page 15 and 16: Antiphospholipid Antibodies: A Conc
Page 17 and 18: Antiphospholipid Antibodies: Major
Page 19 and 20: Antiphospholipid Antibodies: Associ
Page 21: Antiphospholipid Antibody Syndrome:
Page 24 and 25: SSneddon dd syndrome d • Antiphos
Page 26 and 27: Antiphospholipid Antibody and Strok
Page 28 and 29: Serological Diagnosis: Anticardioli
Page 30 and 31: Treatment
Page 32 and 33: PPossible bl New N Treatments T
Page 35 and 36: Hereditary Disorders of Coagulation
Page 37: Hereditary Abnormalities of Clottin
Page 41 and 42: Inherited Thrombophilia and Stroke
Page 43 and 44: Inherited Thrombophilia and Stroke
Page 45 and 46: RRare Causes C of f Stroke S k •
Page 47 and 48: Screening for Coagulopathies: Whom
Page 49 and 50: SSickle kl Cell C ll Hemoglobin H l
Page 51 and 52: SSickle kl Cell C ll Trait T and dD
Page 53 and 54: SStroke k in Sickle S kl Cell C ll
Page 55 and 56: SStroke k in Sickle S kl Cell C ll
Page 57 and 58: Sickle Cell Trait: MRI in Children
Page 59 and 60: SSickle kl Cell C ll Disease: D Tre
Page 61 and 62: Sickle Cell Disease: Other Treatmen
Page 63 and 64: Complications of Sickle Cell Trait
Page 65 and 66: Reversible Cerebral Vasospasm Strok
Page 67 and 68: Reversible Cerebral Vasospasm Syndr
Page 79: Stroke Following Substance Abuse
Page 82 and 83: Stroke Following Substance Abuse
Page 84 and 85: Cocaine • Usually cause stroke in
Page 86 and 87: CCocaine-Induced I d dHHemorrhage h
Page 88 and 89:
Methamphetamine and Related Drugs
Page 93 and 94:
TTreatment: APASS Trial T l • Sub
Page 95:
SSickle kl Cell C ll Disease D •
Page 98 and 99:
TTreatment: APASS Trial T l • Sub
Page 100:
• Encephalopathy and biopsy-prove
Page 103 and 104:
• Check TPA-pubmed CCocaine-induc
Page 106 and 107:
IgA Anticardiolipin Antibodies: Sam
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Unusual Causes of Stroke - Hypercoagulable States and their work-up

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