洪佳麟 - 黃慶璨研究室
洪佳麟 - 黃慶璨研究室
洪佳麟 - 黃慶璨研究室
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8. 甲殼素對黑色素化的 C. neoformans 生物膜之影響<br />
當 C. neoformans 產生黑色素後,對免疫細胞的攻擊、氧化壓力的耐受性皆會提高<br />
[4]。而此實驗發現,黑色素化的 C. neoformans 生物膜對甲殼素的耐受性的確比對照組<br />
高,但實驗結果同時也說明,C. neoformans 所產生的黑色素並不會影響甲殼素的抑菌效<br />
果。<br />
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2. Rabea EI, Badawy ME, Stevens CV, Smagghe G, Steurbaut W. chitosan as<br />
antimicrobial agent: applications and mode of action. Biomacromolecules<br />
2003;4:1457–65.<br />
3. Busscher HJ, Engels E, Dijkstra RJ, van der Mei HC. Influence of a chitosan on<br />
oral bacterial adhesion and growth in vitro. Eur J Oral Sci 2008;116:493–5.<br />
4. Nosanchuk JD, Casadevall A. Cellular charge of Cryptococcus neoformans:<br />
contributions from the capsular polysaccharide, melanin, and monoclonal<br />
antibody binding. Infect Immun 1997;65:1836–41.
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