2010 Neurological Institute Outcomes - Cleveland Clinic

Inpatient Treatment for Depression
The Mood Disorders Inpatient Unit at Lutheran Hospital opened in late January 2008. Data are presented for patients
admitted to this unit in 2010 who consented to complete admission and discharge mood rating scales as part of an
IRB-approved research mood disorder registry. Nearly 70 percent of patients were diagnosed with major depression and
23 percent with bipolar disorder (Type I, II, NOS).
Change in Depressive Symptoms before and after Treatment (N = 251)
2010
Mean Score
40
30
20
10
0
Neurological Institute
Hamilton
Depression Scale
(Range 0 - 52)
Montgomery-Asberg
Depression Rating Scale
(Range 0 - 60)
Admission
Discharge
Both the Hamilton Depression Scale (Ham-D) and the Montgomery-Asberg Depression Rating Scale (MADRS) are widely
accepted and validated instruments to measure severity of depression and response to treatment. Mean group scores on
admission and discharge are displayed for patients admitted to the Mood Disorders Unit from January 1 through December
31, 2010. For both scales, there was a statistically significant reduction in mean severity of depression from admission to
discharge (P = 0.001). Mean duration of hospitalization was 5.6 days.
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