2010 Neurological Institute Outcomes - Cleveland Clinic
2010 Neurological Institute Outcomes - Cleveland Clinic
2010 Neurological Institute Outcomes - Cleveland Clinic
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Depression in 5-Year Increments since MS Diagnosis<br />
<strong>2010</strong><br />
Mean PHQ-9 Score<br />
10<br />
8<br />
6<br />
4<br />
2<br />
0<br />
N =<br />
Mean EQ-5D Score<br />
1.0<br />
0.8<br />
0.6<br />
0.4<br />
0.2<br />
0<br />
N =<br />
<strong>Neurological</strong> <strong>Institute</strong><br />
0-4.99 5-9.99 10-14.99 15-19.99 >20<br />
1,179 846 623 322 354<br />
Years since Diagnosis<br />
Quality of Life in 5-Year Increments since MS Diagnosis<br />
<strong>2010</strong><br />
0-4.99 5-9.99 10-14.99 15-19.99 >20<br />
1,205 855 630 323 356<br />
Years since Diagnosis<br />
Cross-sectional analysis of PHQ-9 scores<br />
shows gradual decline in depression scores<br />
by years since diagnosis with significantly<br />
worse values in individuals with disease<br />
duration of 10 to 14.99 years compared<br />
to those who have had MS for five years or<br />
less (P = 0.007).<br />
EQ-5D scores gradually decline by years<br />
since diagnosis, with significantly worse<br />
values in individuals with disease duration<br />
of 15 to 19.99 years, compared to those<br />
who have had MS for five years or less<br />
(P = 0.025).<br />
67
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