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2010 Neurological Institute Outcomes - Cleveland Clinic

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118<br />

Spinal Disease<br />

Degenerative Spondylolisthesis and Spinal Stenosis<br />

Surgical Treatment<br />

Lumbar degenerative spondylolisthesis is a slippage of one or more vertebral bodies relative to the adjacent vertebral body.<br />

This slippage may cause back and leg pain from neurological compression (stenosis) that may impair walking, standing and<br />

many aspects of daily function. Surgical treatment typically involves decompression and instrumented fusion.<br />

Improvement in Quality of Life Following Laminectomy and Fusion for Spinal Stenosis (N = 37)<br />

<strong>2010</strong><br />

Mean EQ-5D Score<br />

1.0<br />

0.8<br />

0.6<br />

0.4<br />

0.2<br />

0<br />

Before After<br />

Surgery<br />

Quality of life improved following spinal<br />

surgery for spinal stenosis.<br />

Improvement in Depressive Symptoms Following Laminectomy and Fusion for Spinal Stenosis (N = 37)<br />

<strong>2010</strong><br />

Mean PHQ-9 Score<br />

Loss of normal function is often associated<br />

10<br />

with distress. This distress can be measured<br />

8<br />

6<br />

on psychological tests and often manifests<br />

as increased family strife, negative selfperception,<br />

trouble sleeping and depression.<br />

4<br />

Following lumbar laminectomy and fusion for<br />

2<br />

symptomatic stenosis, distress associated<br />

0<br />

Before<br />

Surgery<br />

After<br />

with functional impairments, as measured<br />

by PHQ-9, decreased to levels near those<br />

seen in the general population.<br />

<strong>Outcomes</strong> <strong>2010</strong>

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