Apixaban for the prevention of venous thromboembolism in people ...

Table 5.11 Administration costs Enoxaparin (Table 71 MS-page 167)
Number
of
blood
counts
Cost
of
blood
count
@
Cost of nurse
training
for
30 minutes
*
4 £10.11 £25.00
(87% of
patients)
Home visits
from a
community
nurse
to inject
prophylaxis
13%
of patients
50
Number of
days where
home visit is
required
¥
Community
nurse
#
Total
TKR THR TKR THR
7 29 £27.00 £86.76 £163.98
@unit cost taken from the rivaroxaban STA submission to NICE 49 and updated to 2008/9 costs using the Hospital and
Community Health Service Pay and Price Index 61 (See Appendix 19 MS); *(24-hour ward [costs including qualifications]) 61
¥Treatment duration minus inpatient stay. #(includes district nursing sister, district nurse) - home visit (including wages/salary,
salary oncosts, qualifications, overheads, capital overheads and travel) 61
Health state costs and costs of events
The PE cost comprises of the cost of treating PE that occurs during TKR or THR surgery and
following discharge weighted by the proportion experiencing each event. 63 All Patients
experiencing PE following discharge were assumed to be re-hospitalised.
Distal DVT costs comprised of the cost of treating Distal DVT that occurs during TKR or
THR surgery weighted by the proportion of patients experiencing this event 63 as an inpatient,
plus the cost of treating the cost of distal DVT as an outpatient and readmission weighted by
42, 63
the proportion of patients experiencing each form of treatment.
Proximal DVT costs comprised of the cost of treating Distal DVT that occurs during TKR or
THR surgery weighted by the proportion of patients experiencing this event 63 as an inpatient,
plus the cost of treating the cost of proximal DVT as an outpatient and readmission weighted
42, 63
by the proportion of patients experiencing each form of treatment.
The long term costs, costs applied in the long term Markov model, for PE, DVT, mild to
moderate PTS (year 1/first instance and subsequent years) and severe PTS (year 1/first
instance and subsequent years) were taken from Cohen et al. 2001 64 and inflated to 2008/09
costs using the Hospital and Community Health Services Pay and Price Index. 61 The cost of
caring for and treating disabled patients was taken from Youman et al. 65 and inflated to
2008/09 using the Hospital and Community Health Services Pay and Price Index. 61
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