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NEW NanoCool
Injector
NanoCool Hand-held
or Stereotaxic
Mounted Injector
Foot-Pedal
NanoCool Touch Injector
KEY FEATURES
18ºC for optimal cell viability on any delivery syringe
and eppendorf
20% Increase in Survivability, 76% Lower O 2
Consumption
Rate at 18ºC vs. 37ºC
Flow ramping to reduce injection site blowback
Programmed methods for automatic recall of entire
cell delivery system. Up to 100 methods stored for recall
2 year warranty
High accuracy delivery between 1.3 pl/min to 68ml/min
Preprogrammed bolus injection mode,
just specify injection size and time of dispense
Footswitch activation keeps hands free
NanoCool
Cell Delivery System
When injecting stem cells
viability of cells can be a major
issue. The Harvard Apparatus
NanoCool is the only cooled cell
injection system with optional
cooled and oxygenated vortex
mixer. The injection system and
sample vortex holder are held at
18ºC. The cell delivery is totally
integrated in it operation through
the NanoCool’s microprocessor
system: power, temperature
injection volumes and flow
ramping are all controlled by the
NanoCool’s program. Keeping the
cells at 18ºC instead of 37ºC reduces O 2
consumption of cells by an
average of 76%. The chart to the right shows the different organ
utilization curves.
Temperature effect on O 2
Consumption by Organ Cell Type
Organ Temperature
Oxygen
Comsuption
Change in O 2
Consumption % Change
Kidney 37 to 18 3.7 to 0.9 2.8 75.7
Liver 37 to 18 3.0 to 0.6 2.4 80
Heart 37 to 18 2.4 to 0.7 1.7 70.8
Brain 37 to 18 1.9 to 0.4 1.5 78.9
Muscle 37 to 18) 0.8 to 0.2 0.6 75
Skin 37 to 18 0.4 to 0.1 0.3 75
NanoCool Cell Delivery System Specifications
ACCURACY ± 0.5%
REPRODUCIBILITY ± 0.05%
SYRINGES (MIN./MAX.) 0.05 µl / 1 ml
FLOW RATE:
Minimum
1 ml
Maximum 0.5 µl
INJECTOR HEAD/ACTUATOR, 7 x 1-3/8 x 2 in (17.8 x 3.5 x 5.1 cm)
LxHxW
Order #
PC1 70-3601
Product
IR Temperature Image
NanoCool at 18°C
NanoCool Infusion/Withdrawal Programmable Singe Syringe
24 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com