CHEM01200604012 Dibakar Goswami - Homi Bhabha National ...

NMR of 68a and 68b are shown in Fig. III.1.1, Fig. III.1.2, Fig. III.1.3 and Fig. II.1.4.
The spectral data were commensurate with those reported earlier. 3
Table III.1.1 Course of allylation of 1 using the bi-metallic strategy a
Entry Reagents 1: bromide: metal
: metal salt
Time Yield b
(%)
Product
ratio c
68a : 68b
1 Zn/ Aq. saturated NH 4 Cl 1 : 3.0 : 3.5 : --- 4 h 73.0 3.5 : 96.5
2 CoCl 2 . 6H 2 O, Zn 1 : 3.5 : 3.0 : 3.5 19 h 77.5 6.2 : 93.8
3 CuCl 2. 2H 2 O, Zn 1 : 3.5 : 3.5 : 3.0 14 h 75.4 5.9 : 94.1
4 FeCl 3 , Zn 1 : 3.0 : 3.0 : 3.5 15 min 53.7 7.2 : 92.8
a The reactions were carried out at 5 mmol scale. b Combined yields of isolated pure
products. c Based on isolated yields.
Fig. III.1.1. 1 H NMR spectrum of 68a
80