BioProcess Product Guide - GE Healthcare Life Sciences

pH sensor for Cellbag bioreactor
Cellbag bioreactor can be fitted with an optical pH sensor, a sterile,
single-use “spot” sensor embedded into the bottom of the bioreactor.
To measure pH using the sensor, a WAVEPOD II controller is required for
WAVE Bioreactor 20/50 system.
Cellbag bioreactor pH sensor provides:
• High measurement accuracy with minimal drift over time
• Single-use format
• Optimized for minimum as well as maximum Cellbag working volumes
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Product highlights
For more information, see page 45.
ActiCHO Media System
Fed-batch culture improves the yield and the concentration of highly active recombinant proteins by
continuous supplementation with essential nutrients. PAA has developed an innovative media system for
fed-batch culture of Chinese hamster ovary (CHO) cells that significantly speeds up the entire process. After
a short adaptation phase the optimal feeding strategy can be rapidly identified, allowing early transfer
from shaker flask to protein production in larger scale in a bioreactor.
The ActiCHO Media System is specially optimized to provide high performance and protein yield with
recombinant CHO-DG44 cells in suspension culture. The ActiCHO Media System consists of the adaptation
medium ActiCHO SM, the production medium ActiCHO P, and two matched feeding supplements ActiCHO
Feed-A and ActiCHO Feed-B, and a separate, concentrated stock solution of glucose.
Features of the ActiCHO Media System include:
• Ready-to-use starter kit and scale-up kit
• Chemically defined
• Significant increase in productivity
• Production of proteins with high potency
• Speeds up time to market
For more information, see page 30.
www.gelifesciences.com/bioprocess 19