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BioProcess Product Guide - GE Healthcare Life Sciences

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ReadyToProcess chromatography<br />

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ReadyToProcess<br />

ÄKTA ready and ReadyToProcess columns<br />

are part of the ReadyToProcess platform,<br />

consisting of plug-and-play, ready-touse<br />

solutions for entire chromatography<br />

processes.<br />

ÄKTA ready is a fully automated liquid<br />

chromatography system for process<br />

scale-up and production of materials<br />

for clinical trials. The system operates<br />

with ready to-use, disposable flow paths<br />

that are available in High and Low Flow<br />

Kits. The need for cleaning between<br />

products/batches is eliminated and no<br />

development or validation of cleaning<br />

procedures is required.<br />

Highlights of ÄKTA ready systems include:<br />

• Simple exchange of the complete flow<br />

path removes the need for system<br />

cleaning<br />

• Improved economy and productivity<br />

due to simpler procedures<br />

• Single-use eliminates risk of crosscontamination<br />

between products/<br />

batches<br />

• Scalable processes using UNICORN<br />

ReadyToProcess columns are designed<br />

for seamless scalability, delivering the<br />

same performance level as available in<br />

conventional processing columns such<br />

as AxiChrom and BPG. ReadyToProcess<br />

columns are designed for purification of<br />

biopharmaceuticals for clinical phase I<br />

and II studies. Depending on the scale<br />

of operations, they can also be used for<br />

full-scale manufacturing, as well as for<br />

preclinical studies.<br />

ReadyToProcess columns provide a range<br />

of benefits including:<br />

• Time savings – by eliminating several<br />

time-consuming steps<br />

• Cost savings – by lowering buffer<br />

consumption and reducing cleaning<br />

validation demands<br />

• Process security – robust column<br />

construction and performance<br />

• Scalability – by facilitating conventional<br />

approaches in larger scales<br />

• Reduced cross-contamination<br />

Visit us on the web at<br />

www.gelifesciences.com/readytoprocess<br />

70 www.gelifesciences.com/bioprocess

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