BioProcess Product Guide - GE Healthcare Life Sciences

Application guide – WAVE Mixer
Mixer 20/50ET
In-process blending
In-process intermediates can be mixed and various ingredients can be added.
In-process pooling
In-process samples collected during chromatography or other operations can be pooled together in a
single bag and mixed to form a homogeneous intermediate for sampling and further processing.
Blending for sampling
Mixing stored materials in bags in order to obtain a representative sample for stability and process
optimization studies.
Mixing prior to fill
Mixing stored or collected product prior to dispensing in to final vials, bags, or other containers. Mixing
the bag ensures each aliquot is identical. Using the bag as the mixing container ensures sterility and GMP
operation.
Reconstitution and dissolution
Preparation of media from powdered and concentrated components and preparation of sterile buffers.
In process reactions
Reactions can be carried out in the bag. This may involve adding oxidants or reductants. The headspace in
the bag can be controlled to maintain the desired oxygen level.
Mixer 20/50EHT
Thawing of frozen materials.
Warming blood and other biological fluids.
Maintaining temperature during pooling operations.
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ReadyToProcess
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