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BioProcess Product Guide - GE Healthcare Life Sciences

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Slurry tanks<br />

1<br />

Slurry tanks help to generate a homogenous slurry and thus play a<br />

critical role in ensuring a well-packed column and a robust and efficient<br />

purification process. A well-packed column is characterized by high<br />

resolution (with positive impacts on purity and yield) and high bed stability,<br />

characteristics that help to avoid costly repacking due to poor HETP and<br />

asymmetry.<br />

Slurry tanks provide:<br />

• Homogenous slurry concentrations<br />

• More efficient column packing<br />

• Improved operator safety and process economics<br />

<strong>Product</strong> highlights<br />

For more information, see page 137.<br />

Inline conditioning for process chromatography systems<br />

Current trends in manufacturing biopharmaceuticals have put demands<br />

on securing increased buffer supplies delivered at precise times and at<br />

correct concentration and flow rates. To meet these demands, advanced<br />

technologies such as inline conditioning (IC) have gained increasing<br />

interest, not only because they reduce the need for large storage tanks,<br />

but also because IC can deliver correct solutions for a specific process need<br />

at a lowered total cost of ownership. <strong>GE</strong> <strong>Healthcare</strong> has delivered a wide<br />

range of IC systems, providing a reproducible, fully automated IC process.<br />

Advantages of inline conditioning include:<br />

• Timely buffer delivery<br />

• Automated IC process increases reproducibility<br />

• Allows for use of smaller tanks or disposable bags<br />

• Reduces or eliminates the need for CIP and WFI demands<br />

• Provides better process economics<br />

For more information, see page 144.<br />

www.gelifesciences.com/bioprocess 23

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